Archana Singh-Manoux
  • E-mail :[email]
  • Phone : 3177747410
  • Location : Villejuif, France
Last update 2017-10-08 10:28:23.154

Archana Singh-Manoux PhD, HDR Epidemiology

Course and current status

EMPLOYMENT

Research Director (DR1), INSERM

Honorary Professor, University College London

 

HONOURS & AWARDS

2015: Prix Recherche Inserm

2010: Member, Academia Europaea, The Academy of Europe.

2005: Chair of Excellence Award: French Ministry of Research.

2005: ERC Starting Grant

 

10 KEY PUBLICATIONS (out of a total >280 ), h-index: 51

  • Singh-Manoux A,  Dugravot A, Shipley M, Brunner EJ, Elbaz A, Sabia S, Kivimaki, M. Obesity trajectories and risk of dementia: 28 years of follow-up in the Whitehall II Study. Alzheimers Dement . 2017; pii: S1552-5260(17) 33689-0.  
  • Singh-Manoux A, Fayosse A, Sabia S, Canonico M, Bobak M, Elbaz A, Kivimaki M, Dugravot A. Atrial fibrillation as a risk factor for cognitive decline and dementia. Eur Heart J 2017; 38(34): 2612-2618.
  • Rusmaully J, Dugravot A, Moatti JP, Marmot MG, Elbaz A, Kivimaki M, Sabia S, Singh-Manoux A. Contribution of cognitive performance and cognitive decline to associations between socioeconomic factors and dementia: A cohort study. PLoS Med. 2017 Jun 26; 14(6): e1002334.
  • Sabia S, Dugravot A, Dartigues JF, Abell J, Elbaz A, Kivimäki M, Singh-Manoux A. Physical activity, cognitive decline, and risk of dementia: 28 year follow-up of Whitehall II cohort study. BMJ. 2017; 357: j2709.
  • Singh-Manoux A, Dugravot A, Fournier A, Abell J, Ebmeier K, Kivimäki M, Sabia S. Trajectories of Depressive Symptoms Before Diagnosis of Dementia: A 28-Year Follow-up Study. JAMA Psychiatry. 2017; 74: 712-718.
  • Tuligenga RH, Dugravot A, Tabák AG, Elbaz A, Brunner EJ, Kivimäki M, Singh-Manoux A. Midlife type 2 diabetes and poor glycaemic control as risk factors for cognitive decline in early old age: a post-hoc analysis of the Whitehall II cohort study. Lancet Diabetes Endocrinol. 2014; 2: 228-35.
  • Kaffashian S, Dugravot A, Brunner EJ, Sabia S, Ankri J, Kivimäki M, Singh-Manoux A. Midlife stroke risk and cognitive decline: A 10-year follow-up of the Whitehall II cohort study. Alzheimers Dement 2013; 9: 572-9.
  • Sabia S, Elbaz A, Dugravot A, Head J, Shipley M, Hagger-Johnson G, Kivimaki M, Singh-Manoux A. Impact of smoking on cognitive decline in early old age. The Whitehall II cohort study. JAMA Psychiatry 2012; 69: 627-635.
  • Singh-Manoux A, Kivimaki M, Glymour MM, Elbaz A, Berr C, Ebmeier KP, Ferrie JE, Dugravot A Timing of onset of cognitive decline: results from Whitehall II prospective cohort study. BMJ 2012; 344: DOI: 10.1136/bmj.d7622
  • Singh-Manoux A, Marmot MG, Glymour M, Sabia S, Kivimäki M, Dugravot A. Does cognitive reserve shape cognitive decline? Ann Neurol. 2011; 70: 296–304.

 

 

PROFESSIONAL ACTIVITIES (a selection)

  • 2015 onwards: Board of Directors, Fondation Plan Alzheimer, France.
  • 2015 onwards: Scientific Council, Fondation Recherche Medicale, France.
  • 2011-2014: Deputy Director, French Institute of Public Health (ITMO-Santé Publique)
  • 2011 onwards: Associate Editor, Journal of Epidemiology & Community Health.

 

RESEARCH GRANTS (a selection)

  • 2015-2018Work Package leader on Horizon 2020 (Call: H2020-PHC-2014-single-stage, PHC-31-2014), “FoResight and Modelling for European HEalth Policy and Regulation”.
  • 2009-2015Principal Investigator on grant R01AG013196 (Socio-economic status and heterogeneity in aging) from the National Institute on Aging, NIH, USA.
  • 2009-2015Principal Investigator on grant R01AG034454 (Health behaviors over the adult lifecourse and cognitive aging) from the National Institute on Aging, NIH, USA.
  • 2013-2018Co-Investigator on Grant K013351 (Adult Determinants of Late Life Depression, Cognitive Decline and Physical Functioning - The Whitehall II Study of Ageing) from the Medical research Council, MRC.
  • 2017-2021: Co-Investigator on Grant, “Vascular risk and functional decline in old age: from discovery to translation”. RG/16/11/32334, British Heart Foundation.

 

 

Scientific summary

Epidemiology of ageing and age related diseases (Team 8, CESP), Inserm U1018, https://twitter.com/epiAgeing

Whitehall II study, University College London, http://www.ucl.ac.uk/whitehallII

My research is on the determinants of cognitive decline and dementia with a focus on socioeconomic, occupational, psychosocial, behavioural and biological factors. A second aspect of my work is on the social determinants of health at older ages in order to understand the mechanisms underlying inequalities in health.

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