Tasnime Akbaraly Researcher (Institut National de la Santé et de la Recherche Médicale, Inserm)

Course and current status

ACTUAL POSITION :

- Senior Researcher at Inserm Unit 1098: Molecular Mechanisms in Neurodegenerative Diseases (MMDN)

- Honorary Senior Researcher, Department of Epidemiology and Public Health, University College London, London, UK, since 2009  

PAST POSITION:

2014-2009: Research Fellow, National Institute of Health and Medical Research Unit 1061 neuropsychiatry : epidemiological and clinical research, Montpellier, France

2007-2008: Research Fellow, Dept of Epidemiology & Public Health, UCL, UK

2007: Post doctoral position in MRC Human Nutrition Research, Cambridge, UK

UNIVERSITY DIPLOMA

2013: Habilitation à diriger des Recherches, University Montpellier I, France

2011: University Diploma of Clinical Neuropsychology, University Montpellier I, France. 

2006: PhD Epidemiology and Public Health, University Paris XI, Inserm Montpellier, France.

2003 : Master of Epidemiology, University Paris XI, France.

2000:  Bsc Biochimistry- University Pierre et Marie Curie, Paris VI, France.

HONORS AND RESEARCH SUPPORT

2003-2005: France Alzheimer association grant for the PhD project

2006: French Nutrition Society Grant for the post-doctoral project

2007: Federation of the European Nutrition Societies (FENS) Young Scientist Award for oral communication

2008: International Conference on Alzheimer’s Disease (ICAD). Award for a Travel fellowship

2010: ANR (Association National pour la recherche), coPI of the CRESCENDO (Cognitive REServe and Clinical ENDOphenotype)

2011: Price "Chercheur d'Avenir" from Région Languedoc Roussillon

2012: ARPE funding from Région Languedoc Roussillon

Scientific summary

Research Topic: Determinants of  heterogeneity in aging

Health Behaviour, Metabolic factors and ageing.

- Examining the impact of diet on cognitive,physical functioning and mental health using expertise in nutritional epidemiology and neuropsychology

- Examining the association between type II diabetes biomarkers, cholestrol metabolism and cognitive decline and mental health.

Cognitive Reserve and neuroimaging

- Co-Investigator of the CRESCENDO Projet (Cognitive Reserve and clinical endophenotype), a project in collaboration with Y. Stern (Cognitive Neuroscience Division - Columbia University) .

Based on the hypothesis that CR can attenuate the effects of age-related neural changes via differential expression of functional MRI (fMRI) identified brain networks, the overall theme of the CRESCENDO project is to identify the determinants of heterogeneity in cognitive aging by understanding to what extent CR contributes to explaining this heterogeneity, our approach combines brain imaging biomarkers, neuropsychological assessments, measurements of CR proxies, plasmatic biomarkers of amyloid charge and metabolic disorders.

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