1995-1999 Ph.D. in Neuroscience, University of Lille, France
1994 M.S. in Animal Physiology, University of Paris XI, Orsay, France
1993 B.S. in Biochemistry, University of Paris XI, Orsay, France
2016- : Senior Research Director (“Directeur de Recherche 1ière classe”, DR1), National Institute of Health and Medical Research (Inserm), France
2009- : Co-Director of the International Associated Laboratory NEUROBESE (Inserm - University of Lille 2 - Children's Hospital Los Angeles, University of Southern California, USA).
2006- : Head of the Inserm Research Team “Development and Plasticity of the Neuroendocrine Brain”, Inserm U1172 (former Inserm UMR837, 2006-2014)
2009-2015 Research Director (“Directeur de Recherche 2ième classe”, DR2), Inserm, France.
2002-2009 Associate Researcher (“Chargé de Recherche”), Inserm, France
1999-2002 Postdoctoral Fellow, Division of Neuroscience, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon. Laboratory of Dr. Sergio R Ojeda Laboratory.
1995-1999 French Ministry of Research Doctoral Trainee. Inserm, Lille, France. Laboratory of Dr. Jean-Claude Beauvillain (Inserm U422).
Election to Executive Committees and Advisory Boards
2015-present Treasurer of the Federation of European Neuroscience Societies (FENS)
2014- present Member of the Scientific Council of the French Medical Research Foundation (FRM).
2013-2015 President of the French Society for Neuroendocrinology
2013- 2014 Member of the Institute National de la Recherche Agronomique (INRA) commission for the recruitment of tenured track INRA Research Associate and Directors.
2012-present Member of the Executive Committee of the Federation of European Neuroscience Societies (FENS)
2012-2015 Member of the Council of the International Neuroendocrinology Federation
2012-present Member of the board of the French Glial Cell Club
2008-2009 Treasurer of the French Society for Neuroscience
2009-2011 Treasurer of the French Society for Neuroendocrinology
2006-2011 Member of the board of the French Society for Neuroendocrinology
2006-2009 Member of the board of the French Society for Neuroscience
2006-present Member of the Board of Directors of the Jean-Pierre Aubert Research Center
2008-2013 Member of the Institutional Animal Care and Use Committee of the University of Lille.
2006- 2011 Scientific Director of the “Biserte” animal facility of the federative research Institute of the University of Lille 2 (IFR 114).
Honors and Awards
2014-2017 Inserm award for the Excellence of Research
2007-2012 Contract for translational research, Inserm –Lille County Hospital
2000 “Inserm 2000” postdoctoral fellowship
1996 Doctoral fellowship from the French Ministry of Research
2016- : Associate Editor for Reviews, Neuroendocrinology (IF: 2.6)
2014- : Editorial board of Endocrinology (IF: 4.2)
2011-2013, 2016-present: Editorial board of the Journal of Neuroendocrinology (IF: 3.2)
2008-present : Contributing Editor of the European Journal of Neuroscience (EJN) (IF: 3.0)
2010 Invited editor of the EJN special issue on "Plasticity of Neuroendocrine systems" Volume 32, number 12.
Selected Symposia and Lectures out of 50
The two principal focuses of our research are the Central Control of Energy Homeostasis, and the Neurobiology of Reproduction. Among our pioneering studies are: (i) the demonstration that tanycytes, specialized ependymoglial cells lining the floor of the third ventricle, are responsible for the transport of peripheral metabolic signals such as leptin across brain barriers into the metabolic brain, elucidating a mechanism for leptin resistance in obesity; (ii) the discovery that endothelial cell-derived chemotropic factors of the semaphorin family control GnRH axonal growth in the adult neuroendocrine brain, thus modulating fertility; (iii) the finding that a discrete neuronal population that releases nitric oxide in the preoptic region of the hypothalamus is vital for the rapid integration and transmission of both gonadal and metabolic signals within the neuroendocrine brain, and thus plays a key role in the timing of puberty onset; and (iv) the uncovering that a dramatic switch in miRNA expression patterns in infantile GnRH neurons inverts the balance between inductive and repressive signals, triggering increased hypothalamic GnRH expression and controlling the crucial transition from the early infantile phase, when its levels are low, to the GnRH-fuelled run-up to puberty.