Valérie Lamour
  • E-mail :[email]
  • Phone : +33 3 88 69 48 52 81
  • Location : Strasbourg, France
Last update 2020-06-17 20:05:56.702

Valérie Lamour PhD Structural Biology

Course and current status

Actual position

Associate Professor, Team leader at the IGBMC: Chromatin stability and DNA mobility

Coordinator of Strasbourg University MD-PhD Idex program -  Faculty of Medicine

President of the French national network of MD-PhD programs

Deputy Vice-President for Research, Strasbourg University



2011 Habilitation for Research Direction   (HDR), Strasbourg University 

Since 2009 : Associate Professor, IGBMC-Strasbourg University Hospitals (MCU-PH class 1)

2008: Marie Curie International Reintegration Grant fellow -IGBMC, Strasbourg, France

2003-2008: Postdoctoral fellow, The Rockefeller University, New York, USA

Structural studies of Bacterial RNA polymerase complexes

2000-2003: Postdoctoral associate, IGBMC, Strasbourg France

Thermus DNA topoisomerases structural studies

1999: PhD Structural Biology, Strasbourg University, France

Structural studies of human transcription/repair factors- IGBMC

1994: Chemical Engineer degree, EHICS Strasbourg France

Scientific summary

V. Lamour has joined the IGBMC Integrative Structural Biology Department in 2008 through a Marie Curie International Reintegration grant (FP7). Her research project is aiming at the functional and structural studies of human DNA topoisomerase 2 (Top2) complexes targeted by therapeutic compounds used in cancer treatment. The goal of this study is to identify and study the architecture of Top2-associated complexes targeted by anti-cancer drugs through a combination of biochemical and structural approaches.Since 2014, V. Lamour is co-directing the IGBMC team "Chromatin stability and DNA mobility" with  M. Ruff who focuses on HIV integration complexes. The team uses a combination of structural techniques such as in solution biophysical methods, cryo-electron microscopy, x-ray crystallography with biochemistry and proteomic techniques to address biomedical relevant questions.

The Integrative Structural Biology Department offers state-of-the-art structural biology equipments and access to scientific platforms within the IGBMC. The department is one of the two French nodes for the european infrastructure in structural Biology INSTRUCT-ERIC and coordinator of the french infrastructure FRISBI  for structural biology.

V. Lamour is the coordinator of Strasbourg University MD-PhD Idex program since 2013 and  Deputy Vice-President for Research of Strasbourg University, in charge of Life Sciences and health since January 2017.


The Topo project members:

Valerie Lamour (coordinator)

Christophe Lotz, PhD student

Vita Vidmar, PhD student (co-direction with A. Weixlbaumer's team, IGBMC)

Léa Haas, Master 2

Robert Drillien, researcher

Nina Prats-Torne, MD-PhD administrative assistant  

Former Members of the Topo project:

Arnaud Vanden Broeck, PhD student 2015-2018

Claire Bedez, PhD student 2011-2015

Morgane Gilg, Master student 2015

Claire Batisse, research engineer 2012-2014

Pélagie Fichter, Master student 2013

Geoffrey Gourinchas, Master student 2013

Julie Papillon, PhD student 2008-2012

Albin Simoni, research engineer 2010

The HIV project members :

Marc Ruff (coordinator)

Julien Batisse (postdoc)

Rui Zhu (PhD student)

Nicolas Levy (collaborator)

Robert Drillien (researcher)

Sylvia Eiler (Engineer)

Sylvie Duclaud (technician)




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