2012 - Present: Junior Investigator - INSERM - Chargé de Recherche de 1ère Classe
Université Pierre et Marie Curie UM CR 18
INSERM U1130 – CNRS UMR 8246
2008 - 2012: Post-doctoral Fellow, Eric Nestler Laboratory, Mount Sinai, NY, USA
2006 - 2008: Post-doctoral Fellow, Eric Nestler Laboratory, UTSW, Dallas, USA
2001 - 2005: Graduate student, Bruno Giros Laboratory, Creteil, France
Why some individuals become depressed after a traumatic event while others are resilient?
I'm interested in identifying the molecular adaptations underlying susceptibility and resilience to chronic social stress, which is an ethologically valid approach for the study of stress-induced depressive-like behaviors. I focus primarily on the limbic brain: prefrontal cortex (executive function), hippocampus (cognition) and nucleus accumbens (reward). Behavioral coping to stress depends on specific neuroplastic changes within each limbic structure. Such understanding could help develop better therapeutics for stress-related disorders such as depression and post-traumatic stress disorder.
Expertise: neuropharmacology, neuroanatomy, viral-mediated gene transfer, animal models of depression, anxiety and addiction