Stéphane Romero PhD in Biology, Researcher in Host-Pathogen interaction

Course and current status

Since 2012: Research Assistant (CR2), Inserm, CIRB - Collège de France, Paris (France)

2006-2012: Post-Doctoral Fellow, Unité de Pathogénie Microbienne Moléculaire, Institut Pasteur, Paris (France) and Collège de France, Paris (France)

 “Early steps of Shigella invasion” (Dr Guy Tran Van Nhieu)

2002-2006 Ph.D. in Biochemistry, CNRS, Gif-sur-Yvette (France)

Molecular mechanism of formin, a processive motor of actin assembly” (Dr Marie-France Carlier)

2001-2002: Master (DEA), Laboratoire de Biologie du Développement, UMR 7622, Université Paris VI, Paris (France)

“Cloning and expression of avian VE-Cadherin during ontogenesis” (Pr Dominique Dunon-Bluteau)

Scientific summary

I am a scientist working at INSERM, the French National Institute for Medical Research. I work in the team "Intercellular communication and microbial infections", at the CIRB hosted in the Collège de France, Paris (France). This team gathers scientists working on bacterial pathologies related to invasion of host barriers by different bacteria.

I have developped an interdisciplinar approach (force measurements, cell imaging) to study early interaction between Shigella and the epithelial host cell, which involve bacterial capture by preexistant filopodia. These filopodia retract upon bacterial contact to drive Shigella in contact to the plasma membrane where the bacteria induce its entry into the cell cytoplasm.

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