Sept 2014 – Present
PhD Student – Full-time (PI: Dra Antonella Consiglio)
Institute of Biomedicine of the University of Barcelona (IBUB) – Neural Com. and Diff.
May 2014 – Sept 2014
Laboratory Technician – Full-time (PI: Dra Antonella Consiglio)
Institute of Biomedicine of the University of Barcelona (IBUB) – Neural Commitment and Differentiation
Sep 2013 – May 2014
Laboratory Technician – Part-time (PI: Dr. Cayetano Gonzalez)
Institute for Research in Biomedicine (IRB) Barcelona - Department of Cell Division
Nov 2012 – Jan 2013
Research Assistant/Biologist – Voluntary Basis (PI: Dr. Daniel Hartl)
Harvard University - Department of Organismic and Evolutionary Biology
Aug 2012 – Nov 2012
Research Assistant – Voluntary Basis (PI: Dr. Frank Hirth)
King’s College London - Department of Neuroscience, Institute of Psychiatry
Sept 2010 – Jun 2011
Laboratory Technician – Voluntary Basis (PI: Prof. Kevin O’Bryne)
King’s College London - Reproductive Neurobiology & Early life Origins of Disease Lab, School of Medicine
Sept 2005 - Aug 2006
Healthcare Assistant – Voluntary Basis
Newton-Wellesley Hospital - Maternity Ward, Wellesley, MA, USA
Even with the wealth of current knowledge and the sheer velocity of breakthrough discoveries being made in the field of Neuroscience research, a great deal remains to be learnt about the complex function of the human nervous system and pathalogical development. Since a young age I have been fascinated by the natural world, and over time an interest turned into a hunger for understanding. While the school science curriculum served well to explain many simple phenomena of human physiology, I considered it paramount to seek answers to questions about coordinated movement, sensory mechanisms, control of organ function, the mind hypothesis and memory.
My MSc in Neuroscience has given me the techniques necessary to investigate the development of neurodegenerative diseases in order to find suitable therapies. My thesis titles, "Drosophila Models of Neurodegeneration:The role of EAAT1 in TDP-43 related Motor Neuron Disease formation", has given me the knowledge and understanding needed to further investigate ALS.
I am now doing my PhD in Dr. Antonella Consiglio's laboratory in the Institute of Biomedicine at the Universoty of Barcelona, Spain. My project focuses on the roles astrocytes play during Parksinson's disease by using patient-specific induced pluripotent stem cells (iPSC). In collaboration with Giulia Carola (current labmate), we have developed a co-culturing system with dopaminergic neurons and astrocytes, enabeling us to have a direct birds-eye view in the PD patient's brain.
• Critically analyses
• Motivated by scientific discoveries
• Hard working
• Social and communicative
• Quick thinker
Highly flexible and able to move anywhere in Europe, North America and Canada.
Diaper, DC, Adachi, Y, Lazarou, L, Greenstein, M, Simoes FA, di Domenico, A, Solomon, A, Lowe, S, Al Subaie, R, Cheng, D, Buckley, S, Humphrey, DM, Shaw, CE, Hirth, F (2013) Drosophila TDP-43 dysfunction in glia and muscle cells cause cytological and behavioural phenotypes that characterize ALS and FTLD. Human Molecular Genetics, May 31.
Grachev, P, Li, X-F, Kinsey-Jones, J, di Domenico, A, Millar, R, Lightman, S, O'Byrne, K (2012) Suppression of the GnRH pulse generator by neurokinin B involves a kappa-opioid receptor-dependent mechanism. Neuroendorinology, 153(10):9894-904.