CURRENT PROFESSIONAL POSITION:
Tenured researcher, CNRS section 26
Group ‘Neurogenesis and pathophysiologie’ leaded by Dr. Djoher Nora Abrous, INSERM U862 ‘Pathophysiology of neural plasticity’ leaded by Dr. Pier Vincenzo Piazza
1998 Ph.D. in Neuroscience and Pharmacology, University of Bordeaux 2, France
1995 Master’s degree in Neuroscience and Pharmacology, U Bordeaux 2, France
1994 Teaching diploma Biochemistry, Ecole Normale Supérieure Cachan, Paris
1993 Bachelor in biochemistry, University Paris VII, Paris, France
Understanding the mechanisms that governs memory processes and affective states under both physiological and pathological conditions represents a major issue in modern neuroscience as it will certainly assist in the development of therapeutic tools. In this context, my research focuses on a potential mechanistic substrate, i.e. adult neurogenesis, as it has been proposed as a promising target for the prevention and treatment of memory and affective disorders. This neurogenesis takes place in 2 discrete regions of the adult brain, i.e. the dentate gyrus of the hippocampal formation, hence its relevance for memory and affective disorders, and the olfactory bulb. My research aims at characterizing the functional roles as well as the environmental regulation of newborn neurons in both areas. To this end, we are using mice models to analyze the contribution of hippocampal neurogenesis to memory processes and mood disorders from early postnatal development until adulthood, and to assess the function role and the regulation of bulbar neurogenesis. It is expected that these lines of research will bring significant contribution to our understanding of memory and mood disorders.