Julie Klein
  • E-mail :[email]
  • Phone : +33 5 31 22 40 70
  • Location : Toulouse, France
Last update 2015-11-09 16:39:04.562

Julie Klein PhD Renal pathophysiology, INSERM Researcher

Course and current status

ACTUAL SITUATION Scientist INSERM U1048/Team 12, Toulouse, France

RESEARCH

2014 Postdoctoral fellow at the School of Computer Science, University of Manchester, UK 

2013-2014 Postdoctoral fellow at Mosaiques Diagnostics and Therapeutics GmbH, Hannover, Germany

2012-2013 Postdoctoral fellow at the School of Computer Science, University of Manchester, UK

2009-2011 Postdoctoral fellow at INSERM U1048, Toulouse, France

2005-2009 PhD student at INSERM U858, Toulouse, France  

EDUCATION

2005-2009 PhD in Pharmacology and Pathophysiology, Summa cum laude, Université Paul Sabatier, Toulouse, France

2004-2005 Certificate of Advance level Study in Biology and Biotechnologies, Université Paul Sabatier, Toulouse, France

2003-2004 Master in Cellular Biology and Physiology, Université Paul Sabatier, Toulouse, France

2000-2003 Bachelor’s degree in Cellular Biology and Physiology, Université Paul Sabatier, Toulouse, France

TEACHING

2015 Research University for Young Nephrologists, Lyon.

2006-Present Lecturer (non permanent position) in Cell Biology, Molecular Biology, Animal Physiology, Histology for medical students and biology student (1st year to 5th year)

Université Paul Sabatier, Toulouse France and Conservatoire National des Arts et Métiers (CNAM), Toulouse, France

FELLOWSHIPS AND GRANTS

2012-2013 Postdoctoral Fellowship, FP7 Marie-Curie, Intra-European Mobility

2012-2013 Postdoctoral Fellowship, EMBO/ERA-EDTA

2008-2009 Research Fellowship, Fondation pour la Recherche Médicale

2005-2008 PhD Grant, French Board of Education and Research

PRIZES AND AWARDS

2015 Research Award, French Society of Nephrology

2014 Research subvention for clinical nephrology research, French Society of Nephrology/Genzyme

2011 Lucien Babonneau Award for Diffusion of the scientific knowledge, The Academy of Sciences, Toulouse, France

2008 1st Prize for the best oral communication, Takis Anagnostopoulos Symposium, Paris

2008 1st Prize for the best poster communication, Royal Society of Medecine, London, UK

2007 1st Prize for the best poster communication, Federative Research Institutes Meeting, Toulouse, France

Scientific summary

Julie Klein received her PhD from the University Paul Sabatier, Toulouse, France, in 2009. From 2009 to 2014 she worked as a post-doctoral fellow in the field of proteomics and bioinformatics in chronic kidney disease and was recruited as a researcher at the Renal Fibrosis Lab, INSERM U1048, Toulouse in 2014.

Julie Klein main domains of expertise are:

- Bioinformatics tools and databases (http://www.kupkb.org/; http://www.proteasix.org/)

- Clinical proteomics

- Cardiovascular complications of chronic kidney disease

- Mechanisms of chronic kidney disease

- Urinary biomarker

Selected Publications:

Glorieux G, Mullen W, Duranton F, Filip S, Gayrard N, Husi H, Schepers E, Neirynck N, Schanstra JP, Jankowski J, Mischak H, Argilés A, Vanholder R, Vlahou A, Klein J.  New insights in molecular mechanisms involved in chronic kidney disease using high-resolution plasma proteome analysis. Nephrol Dial Tranplant. 2015.

Filip S, Pontillo C, Peter Schanstra J, Vlahou A, Mischak H, Klein J. Urinary proteomics and molecular determinants of chronic kidney disease: possible link to proteases. Expert Rev Proteomics. 2014 Oct;11(5):535-48. doi: 10.1586/14789450.2014.926224. Epub 2014 Jun 24.

Klein J, Lacroix C, Caubet C, Siwy J, Zürbig P, Dakna M, Muller F, Breuil B, Stalmach A, Mullen W, Mischak H, Bandin F, Monsarrat B, Bascands JL, Decramer S, Schanstra JP. Fetal urinary peptides to predict postnatal outcome of renal disease in fetuses with posterior urethral valves (PUV). Sci Transl Med. 2013 Aug 14;5(198):198ra106. doi: 10.1126/scitranslmed.3005807.

Klein J, Eales J, Zurbig P, Vlahou T, Mischak H, Stevens R. Proteasix: a tool for automated and large-scale prediction of proteases involved in naturally-occurring peptide generation. Proteomics, 2013 Apr;13(7):1077-82. doi: 10.1002/pmic.201200493. Epub 2013 Feb 26

Klein J, Jupp S, Moulos P, Fernandez M, Buffin-Meyer B, Casemayou A, Chaaya R, Charonis A, Bascands JL, Stevens R, Schanstra JP. The KUPKB: a novel Web application to access multiomics data on kidney disease. FASEB J. 2012 May;26(5):2145-53. doi: 10.1096/fj.11-194381. Epub 2012 Feb 17.

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