After a doctorate in veterinary medicine, Cécilia Samieri hold a PhD in epidemiology from University of Bordeaux (France) in 2009. She completed a post-doctoral fellowship at the Channing Division of Network Medicine, Harvard Medical school (Boston, USA). Then, she returned to France with a young investigator grant awarded by the Fondation Plan Alzheimer (which managed research measures of the 3rd French National Alzheimer Plan 2008-2012). In Janurary 2015, she joined the INSERM (French National Institue for Health) as a Senior Researcher, and is currently working in the research center INSERM U897 (Bordeaux).
Cécilia Samieri's research has mainly focused on the epidemiology of aging, with the aim of understanding how environmental factors, in particular diet, influences the aetiology of brain diseases and conditions in aging, in particular dementia and cognitive decline. She has been working on several large cohorts on dementia and cognitive decline, including the French Three-City study and Harvard cohorts (Nurses' Health Study and Women's Health Study), and she has developed, over the past few years, a multidisciplinary epidemiological expertise across nutrition, neurosciences, biostatistics and brain imaging. She is currently leveraging her collaborative network to explore gene-by-nutrient interactions in cognitive decline and dementia across several large US and French cohorts of older subjects. Since environmental factors have a pleiotropic role in health, a broader perspective of her research has recently focused on environmental strategies to maintain overall health in aging. For example, she has contributed to demonstrate the impact of a healthier diet in midlife (eg., a Mediterranean diet) for healthy aging.
There is increasing evidence that a number of age-related diseases originate in early life. Hence, it has become more and more evident that future brain aging research should move on early prevention. Yet, the optimal strategy, including the most critical window of opportunity for prevention, remains to be elucidated. To inform early mechanisms underlying the relation of the environment and brain health, Cécilia Samieri is currently extending her research to the investigation of environmental factors (in particular diet and lifestyle) and brain structure and function of young adults in a large ongoing cohort of French students (i-Share). She is the PI of nutrition research in the cohort.