Aminata TOURE
  • E-mail :[email]
  • Phone : +33 1 44 41 23 10
  • Location : Paris, France
Last update 2017-04-14 10:17:49.983

Aminata TOURE PhD Molecular and Cellular Biology

Course and current status

Current Position

Directrice de Recherche CNRS (DR2).

Institut Cochin. INSERM U1016, CNRS UMR 8104, Université Paris Descartes

Equipe Genomique, Epigenetique et Physiopathologie de la Reproduction

 

Education & Degrees

2008    HDR (Habilitation à Diriger des Recherches).

2000    PhD. Molecular and Cellular Biology. Université Paris V

1996    DEA (MASTER 2) Molecular Biology-Development-Pathology. Université Paris V

1995    Maitrise (MASTER 1) Genetics. Université Pierre et Marie Curie, Paris VI

 

Scientific career

2013 – present     Directrice de Recherche CNRS DR2. Institut Cochin, Paris

2008 – 2012         Chargée de Recherche CNRS CR1. Institut Cochin, Paris

2004 – 2008         Chargée de Recherche CNRS CR2. Institut Cochin, Paris

2000 – 2004         Post-Doctorate. Laboratory P. Burgoyne. MRC. London. UK

1996 – 2000         PhD. Laboratory G. Gacon. INSERM U257, Paris.

Scientific summary

My research topic concerns the characterization of the molecular mechanisms, which control sperm flagellum assembly and sperm motility. For this purpose we combine cell biology, molecular biology and mouse genetics. In addition, in collaboration with the department of Reproductive Biology (Cochin hospital), we develop several programs aiming at defining the pathophysiological mechanisms associated with human male infertility.

Selection of recent publications:

El Khouri E, Thomas L, Jeanson L, Bequignon E, Vallette B, Duquesnoy P, Montantin G, Copin B, Dastot-Le Moal F, Blanchon S, Papon JF, Lorès P, Yuan L, Collot N, Tissier S, Faucon C, Gacon G, Patrat C, Wolf JP, Dulioust E, Crestani B, Escudier E, Coste A, Legendre M, Touré A*, Amselem S*. Mutations in DNAJB13, Encoding an HSP40 Family Member, Cause Primary Ciliary Dyskinesia and Male Infertility. Am J Hum Genet. 2016 Aug 4;99(2):489-500.  

Dirami T, Rode B, Wolf JP, Gacon G, Dulioust E, Touré A. Assessment of the frequency of sperm annulus defects in a large cohort of patients presenting asthenozoospermia. Basic Clin Androl. 2015 Nov 15;25:10.

Chikhoune A, Stouvenel L, Iguer-Ouada M, Hazzit M, Schmitt A, Lorès P, Wolf JP, Aissat K, Auger J, Vaiman D, Touré A. In-vitro effects of Thymus munbyanus essential oil and thymol on human sperm motility and function. Reprod Biomed Online. 2015 Sep;31(3):411-20.

Lorès P, Vernet N, Kurosaki T, Van de Putte T, Huylebroeck D, Hikida M, Gacon G, Touré A. Deletion of MgcRacGAP in the male germ cells impairs spermatogenesis and causes male sterility in the mouse. Dev Biol. 2014 Feb 15;386(2):419-27.  

Dirami T, Rode B, Jollivet M, Da Silva N, Escalier D, Gaitch N, Norez C, Tuffery P, Wolf JP, Becq F, Ray PF, Dulioust E, Gacon G, Bienvenu T, Touré A. Missense mutations in SLC26A8, encoding a sperm-specific activator of CFTR, are associated with human asthenozoospermia. Am J Hum Genet. 2013 May 2;92(5):760-6.

Rode B, Dirami T, Bakouh N, Rizk-Rabin M, Norez C, Lhuillier P, Lorès P, Jollivet M, Melin P, Zvetkova I, Bienvenu T, Becq F, Planelles G, Edelman A, Gacon G, Touré A. The testis anion transporter TAT1 (SLC26A8) physically and functionally interacts with the cystic fibrosis transmembrane conductance regulator channel: a potential role during sperm capacitation. Hum Mol Genet. 2012 Mar 15;21(6):1287-98.

Image d’exemple