DEVIN team leader in Toulouse NeuroImaging Center (ToNIC INSERM unit- UMR1214)
DEvelopment and Validation of biomarkers in MRI and Nuclear medicine (DEVIN)
Full time Researcher (CR1) at INSERM 825 unit, Toulouse, France (since november 2010)
~Professional experience ~
2013 -2015 Co-founder and Chief Biomed Advisor of QuantaVita srl
2004-2010 Post-doc fellow in Radiology department of Santa Lucia Foundation (Rome, Italy). Manager of magnetic resonance translational studies.
2015 HDR, Diploma to enable research supervision (University of Paul Sabatier, Toulouse)
2004 PhD in Neuropsychology and Neuroimaging entitled: "Verb Processing : Neuropsychology study in subcortical pathologies & Neuroimaging and Pharmacological study in healthy subjects"
Supervisors.: Pr D. Cardebat et Pr O. Rascol University of Le Mirail, Toulouse, France 2000 Master’s degree in Neuropsychology, University of Paul Sabatier, Toulouse, France 1999 Bachelor’s degree in Neuroscience, University of Paul Sabatier, Toulouse, France
My main objectives are to develop and adapt advanced neuroimaging techniques to translational and clinical research. I developed multimodal MRI in collaboration with IRCCS Santa Lucia (Rome, Italy) . The concept is based on the combination of MRI parameters sensitive to different tissue characteristics (e.g. volume atrophy, iron deposition, and microstructural damage). My recent findings reveal that this innovative approach, the multimodal MRI, is able to discriminate PD patients from healthy control subjects with high accuracy (Peran et al.,Brain, 2010).
Nemmi F, Sabatini U, Rascol O, Péran P. Parkinson's disease and local atrophy in subcortical nuclei: insight from shape analysis. Neurobiol Aging. 2015 Jan;36(1):424-33.
Nemmi F, Saint-Aubert L, Adel D, Salabert AS, Pariente J, Barbeau EJ, Payoux P, Péran P. Insight on AV-45 binding in white and grey matter from histogram analysis: a study on early Alzheimer's disease patients and healthy subjects. Eur J Nucl Med Mol Imaging. 2014 Jul;41(7):1408-18.
de Pasquale F, Sabatini U, Della Penna S, Sestieri C, Caravasso CF, Formisano R, Péran P. The connectivity of functionalcores reveals different degrees of segregation and integration in the brain atrest. Neuroimage. 2013 Apr 1;69:51-61.
Péran P, Cherubini A, Assogna F, Piras F, Quattrocchi C, Peppe A, Celsis P, Rascol O, Démonet JF, Stefani A, Pierantozzi M, Pontieri FE, Caltagirone C, Spalletta G, Sabatini U. Magnetic resonance imaging markers of Parkinson's disease nigrostriatal signature.Brain. 2010
Cherubini A, Péran P., Spoletini I., Di Paola M., Di Iulio F., Hagberg G.E., Sancesario G., Gianni W., Bossù P., Caltagirone C., Sabatini U., Spalletta G. Combined Volumetry and DTI in Subcortical Structures of Mild Cognitive Impairment and Alzheimer’s Disease Patients. Journal of Alzheimer disease 2010
Cherubini A, Péran P, Caltagirone C, Sabatini U, Spalletta G. Aging of subcortical nuclei: microstructural, mineralization and atrophy modifications measured in vivo using MRI. Neuroimage. 2009 Oct 15;48(1):29-36.
Péran P, Cardebat D, Cherubini A, Piras F, Luccichenti G, Peppe A, Caltagirone C, Rascol O, Démonet JF, Sabatini U. Object naming and action-verb generation in Parkinson's disease: A fMRI study. Cortex. 2009 Mar 14.
Péran P, Cherubini A, Luccichenti G, Hagberg G, Demonet JF, Rascol A, Celsis P, Caltagirone C, Spalletta G, Sabatini U. (2009). Volume and iron content in basal ganglia and thalamus. Hum Brain Mapp. 2009 Jan 26
Péran P, Hagberg G, Luccichenti G, Cherubini A, Brainovich V, Celsis P, Caltagirone C, Sabatini U. Voxel-based analysis of R2* maps in the healthy human brain. J Magn Reson Imaging. 2007 Dec;26(6):1413-20.
Péran P, Rascol O, Démonet JF, Celsis P, Nespoulous JL, Dubois B, Cardebat D Deficit of verb generation in nondemented patients with Parkinson's disease. Mov Disord 2003 Feb;18(2):150-6
2016 - 26 november – OHBM 2nd Alpine Chapter symposium Do multimodal MRI parameters enhance the diagnostic accuracy of Parkinson's disease and atypical parkinsonism? Salzburg (Austria)
2016 - 8-10 June - Congrès de Psychiatrie et Neurologie de Langue Française L’IRM multimodale : applications en psychiatrie Toulouse (France)
2015 - 13 november - Course Report: Bridges and Boundaries in Movement Disorders: The Role of Neuroimaging Multimodal MRI in Parkinson’s disease and parkinsonian syndromes Pisa (Italy)
2015 - 20-23 June- 1st Congress of the European Academy of Neurology, Multimodal MRI markers discriminate Parkinson’s disease from multiple system atrophy patients. Berlin (Germany)
2012 -19-20 March - 4th International congress on multiple system atrophy, MRI multimodal approach: a valuable marker of MSA? Toulouse (France)
2006 - 18-20 october 2nd Meeting of the European Societies of Neuropsychology, Semantic of Action and Mental Representation of Action: common neural substrates? Toulouse (France)
2004 - 24-27 October - Mental dysfunction in Parkinson’s disease Verb Processing In Parkinson ‘s Disease And Huntington’s Disease Salzburg (Austria)
- Radiology translationnal research, Santa Lucia Fundation, Roma , Italy (Pr Sabatini,Dr. F. de Pasquale)
- Neuroimaging Research Unit, Institute of Neurological Sciences, National Research Council, Germaneto, Italy (Dr. A. Cherubini).
- Neurology Department of University Hospital “Marqués de Valdecilla” Santander, Spain (Dr. M. Sierra).