Pierre Sicard
  • E-mail :[email]
  • Phone : 04 67 41 52 32
  • Location : Montpellier, France
Last update 2019-08-26 10:55:40.0

Pierre Sicard PhD Cardiovascular physiopathology

Course and current status

I obtained from the University of Burgundy, a PhD in Cardiovascular physiology (under the supervision of Pr ROCHETTE) in October 2007. During my PhD I studied the interplay between oxidative stress, hypertension and their consequences on the heart. We published four publications from my PhD work in peer review journals (e.g. British Journal of Pharmacology, American journal of hypertension) and we have confirmed the major importance of oxidative stress during cardiovascular pathology. On top of this, I have accumulated three years of experience in clinical research in cardiology, which has given me the opportunity to work closely with cardiologists, biologists and bioengineers.

In November 2007, I joined Michael MARBER’s group at King’s College London for my first postdoctoral position. My aim was to study the importance of p38 MAPK isoforms during myocardial infarction. In addition, we discovered a new biomarker (MYBP-c) for the early detection of myocardial infarction in patient.

In 2011, I obtained 3 grants from different French research foundations (310Keuros) and took the opportunity to develop my own project at the Institute of Metabolic and Cardiovascular Diseases in Toulouse, France. The aim of this bench to bedside study was to determine the potential contribution of Gadd45 proteins in post-infarction remodeling. To do so, I developed a number of specific experimental models (e.g. adult cardiomyocytes isolation and culture, Langendorff perfusion, PV-loop analysis, echocardiography and speckle tracking using the Vevo2100, in an in vivo model of myocardial infarction in mice. Following this work, I now hold two patents for treating and diagnosing myocardial infarction and heart failure.

Since 2016, I hold a permanent position at INSERM Montpellier (PhyMedExp Lab) as a research engineer. I am in charge of the ultrasound/photoacoustic facility (Vevo LAZR-X)

To date, I am the author and co-author of more than 56 publications 

Scientific summary

My main scientific interest is focused on experimental model of myocardial infarction and new imaging modality using photoacoustic and high resolution ultrasound. I am in charge of the ultrasound/photoacoustic facility (Vevo LAZR-X) at IPAM/Biocampus (Iso9001)


Actual research projects:

- Whole body photoacoustic imaging to evaluate multi-organ failure after myocardial infarction


- Right ventricular myocardial infarction and biventricular interaction

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