Michel Lagarde
  • E-mail :[email]
  • Phone : +33472438240
  • Location : Villeurbanne, France
Last update 2019-07-23 16:23:35.356

Michel Lagarde University Professor Emeritus at INSA-Lyon (Université de Lyon)

Course and current status

Doctorate in Biochemistry (1974), Doctorate es-Sciences (1979), Doctorate in Human Biology (1983).

Post-doc London (1980), Short sabbaticals: London (1981-1983), Chicago (1984), Michigan State Univ (1993), Univ California San Diego (2006).

Research Assistant Pasteur Institute (1972-1976), Research Scientist INSERM (1976-1987), University Professor (1987-).

Head of an INSERM Unit (1988-2006), Founder of IMBL and President of the Board (2002-2012), Honorary President of IMBL since 2013, Scientific Director of the LISA Carnot institute (2007-2012), Scientific Director of the IBiSA Functional Lipidomics platform (2006-2014), Vice-President of INSA-Lyon (2011-2014). Founder and president of the Spin Off LipTher (2015).

President of GERLI (1994-2001), of ICBL (2006-2009), of ISSFAL (2006-2009).

Normann Medal (2008), Chevreul Medal (2010), European Lipid Science Award (ELSA) (2016), ISSFAL Fellow (2016).

Member of the "Académie des Sciences, Belles-Lettres et Arts de Lyon" (2014).

Member of the New York Academy of Sciences (2018).

Scientific summary

Research interest in lipid mediators such as prostanoids and lipoxygenase products from various polyunsaturated fatty acids (PUFA) of nutritional value, especially omega-3 PUFA; their biosynthesis and biological activities in blood and vascular cells. Lipid peroxidation associated with aging and diabetes in the frame of vascular diseases. Metabolic fate of PUFA (esterification into complex lipids and oxygenation) in humans and human cells in vitro. Biological activity of oxygenated derivatives of PUFA. Imaging of membrane lipids. Fluxolipidomics.

Targeting tissues, especially the brain, with polyunsaturated fatty acids-containing structured phospholipids. Application to neurodegenerative diseases.

Around 500 publications according to Web of Science (H factor: 53) and 9 patents. 

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