Permanent Investigator at Inserm (The National Institute of Health and Medical Research)
UMR_S 1134 "Integrated Biology of the Red Cell"
2006-present: Researcher (CR1) at Inserm
2002-2006: Researcher (CR2) at Inserm
2001-2002: Post-doctoral fellow, University of California San Francisco
1996-2001: Teaching assistant, University Paris Diderot – Paris 7
2011: Habilitation à Diriger des Recherches, University Paris Diderot – Paris 7
2000: PhD in Human Genetics, University Paris Diderot – Paris 7
Adhesion molecules are expressed on the surface of differentiating erythroblasts and play an important role during erythropoiesis. A subset of these molecules persists on the surface of circulating red blood cells and is at the origin of abnormal cell-cell interactions in red cell disorders such as Sickle Cell Disease, Polycythemia Vera and Hereditary Spherocytosis.
Our work aims to identify the membrane proteins involved in such interactions and to characterize the signaling cascades regulating their adhesion function under pathophysiological conditions.