Frédéric Causeret
  • E-mail :[email]
  • Phone : +33 1 42 75 45 68
  • Location : Institut Imagine & Centre psychiatrie et neurosciences, Paris, France
Last update 2018-01-24 11:59:11.745

Frédéric Causeret PhD Developmental Neurobiology

Course and current status

2018 onwards: Inserm researcher in the team of Alessandra Pierani. Institut Imagine and Centre Psychiatrie et Neurosciences - Paris, France.

2012-2017: Inserm researcher in the team of Alessandra Pierani. Institut Jacques Monod - Paris, France.

2007-2011: Inserm Junior post-doctoral fellow in the team of Alessandra Pierani. Institut Jacques Monod - Paris, France.

2004-2007: EMBO post-doctoral fellow in the team of Margareta Nikolić. Imperial College London - London, UK.

2001-2004: PhD student under the direction of Evelyne Bloch-Gallego. Inserm U106 and Institut Cochin - Paris, France.

Scientific summary

I am interested in understanding the cellular and molecular mechanisms of brain development, especially neurogenesis, cell survival, neuronal migration and axon guidance. I use a wide range of approaches including mouse genetics, histology, neuronal culture, biochemistry and molecular biology to better understand the signalling pathways involved in these processes and how their disregulations can lead to pathologies.

Past and recent findings:

- Function and evolution of the Dbx1 transcription factor in the cerebral cortex

- Identification of Kremen1 as a novel dependence receptor

- Signalling function of dbx1-derived cells in forebrain survival and patterning

- Involvement of cytoskeletal regulators (Rho, Rac1, Cdc42, Pak1, Cdk5, Neurabin1) in axon growth & guidance and neuronal polarity & migration

- Role of Netrin-1 and Slits in the migration and survival of precerebellar neurones

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