• E-mail :[email]
  • Phone : +33 1 44 27 82 03
  • Location : Paris, France
Last update 2017-07-15 17:29:02.503

Jagadeesh Bayry DVM, PhD (Immunology), HDR

Course and current status

2010- Present:  Chargé de Recherche-CR1 (Equivalent of Associate Professor) at Institut National de la Santé et de la Recherche Médicale (INSERM).

2006-10: Chargé de Recherche-CR2 (Equivalent of Assistant Professor) at Institut National de la Santé et de la Recherche Médicale (INSERM).

Additional posts

2015-16:  Member of European Research Council (ERC):  Panel Member of a Consolidator Grant Panel LS6 “Immunity and Infection”

2015:   Scientific Council Member: INNO INDIGO partnership Programme on “Diagnostic and interventions in chronic non-communicable diseases”: Innvovation-driven initiative for the development and integration of Indian and European research (India and Belgium,  Estonia, France, Germany, Norway, Portugal)

Post-doc Research

2006: INSERM U681, Centre de Recherche des Cordeliers, 75006, Paris

2004-2006: University of Oxford, The Edward Jenner Institute for Vaccine Research, UK.

2003-2004: INSERM Unit 430 – Institut Biomedical des Cordeliers, Paris, France.

1999-2000: Poultry Diagnostic and Research Center, Pune, India.

Scientific summary

The maintenance of immune equilibrium and optimum immune response to pathogens implicate a co-coordinated cross-talk between antigen presenting cells such as dendritic cells (DCs), and cells of adaptive immunity T and B cells. A dysregulation in the dialogue between immune mediators results in a break in the immune tolerance leading to immunopathological situations including autoimmunity.

My major research interests are deciphering the role of B and regulatory T cells (Tregs) and circulating normal IgG in maintenance of immune tolerance. The anti-inflammatory functions of circulating normal IgG is being studied via therapeutic intravenous immunoglobulin (IVIG), a pooled normal human IgG preparation obtained from several thousand healthy donors and is one of the highly solicited immunotherapies for autoimmune and inflammatory diseases.

In addition, as secondary research domain, we are  exploring the immune evasion mechanisms of two respiratory pathogens: Aspergillus fumigatus and Mycobacterium tuberculosis.

Image d’exemple