Current Position: Research Director INSERM, Cancer Research center of Lyon, CRCL, INSERM U1052 CNRS UMR5286, lyon, France
1992- PhD in Virology, University PARIS VII, France
2001- Habilitation à Diriger les recherches, UNiversity of Nantes, France
1989-1992 PhD training, Molecular and Cellular Immuno-Virology laboratory, CNRS UMR30, Lyon France
1992-1994 Post-doctoral position, Retroviruses and Gene Transfer laboratory, Pasteur Institute, Paris, France
1994-1995 Research Scientist, Somatix Therapy Corporation, Alameda, CA USA.
1995-2006 Research Scientist, Gene Therapy laboratory, INSERM U649, Nantes, France
2006-2012, Research Director, Team Leader, Human Virology Department, INSERM U758, ENS Lyon, France (Avenir group from 2007 to 2011)
2013-2015, Research director,Team leader, CIRI, INSERM U1111 CNRS UMR5308, ENS Lyon, France.
2013- 2015, Director of the Franco-Argentinean International Associated Laboratory (LIA) "Devenir"
2000 Journal of Gene Medecine Young Investigator Award, European Society for Gene Therapy
2006 Selection for Avenir program, INSERM renewal in 2010)
Despite an effective vaccine, chronic infections with HBV remain a major public health problem worldwide, and represent the first cause of liver cancer. Indeed, even if current antivirals generally lead to the reduction of viremia in the blood of patients, the liver viral clearance is rarely obtained, thus making life-long therapy mandatory. Our research program is focused on the identification of novel cellular factors critical for HBV replication and pathogenesis to develop new therapeutic strategies.