since 1999 at the Hospital Saint-Louis, Paris
Permanent position at the Inserm as 1st Class Research Engineer, in the laboratory Inserm, UMR_S1165 actually, located in Paris at the Institute of Haematology (IUH) where I am in charge of a laser microdissection Unit and of the animal histopathology Department.- Skills in Laser Microdissection technology since 1999 Coordinator and in charge of the French Micro-Laser network since 2001, a national network composed of one hundred members offering scientific meetings 2-3 times a year and technological training (Besançon, Bordeaux and Rouen).
Originally a long academic career around the Biochemistry and Animal Physiology starting in 1978 at the Paris-Sud University (University Paris XI, Orsay) up to 1984. A research training in the field of molecular biology techniques then at the Laboratory of Enzymology (CNRS in Gif-sur-Yvette) under the direction of Dr. José Salat-Trepat which has been realized by obtaining a degree in Human Biology focused on digestive physiology (DERBH) in 1986.
Then in 1992, I got my PhD on the study of proteins in the acute inflammatory response observed in rats in which I conducted a one-year stay in 1990 on a scholarship Inserm training based on IL-6 studies in a European laboratory of international renown in Aix-la-Chapelle (RWTH Klinikum, Institute für Biochemie, Aachen, Germany).
Two post-doctoral fellowships followed afterwards from 1992 to 1998 at the Institut Gustave-Roussy (Villejuif), on the cytokine-dependant inflammatory process for the former and on the apoptosis study for the latter, allowed me to acquire additional knowledge in the field of cell culture and proteomic analysis (Western blotting, IP, IHC, ...).
I joined INSERM with a permanent position in 1999 until now as Responsible for the management of the Department of Animal Models Pathology at the Institute of Hematology (Hospital Saint-Louis, Paris), and as Headleader since 2001 of the laser Microdissection Unit.
Since 2001 I found the first network dedicated to the laser microdissection technology. This network includes just over one hundred members now and meets two or three times a year since 2009 through the organization of focused meetings on morphological and molecular analysis of very small sizes biological samples (biopsied under control imaging or microdissected), in regard to all species (human, animal and plant) and all pathologies.
In November 2014, I supported the organization of lectures given as part of the course "Pathological and Therapeutic Macromolecules" within the Master 2 BC2T (Biochemistry, Cells, Therapeutic targets) of the University Paris-Diderot. All these lectures lasting three full days attempts to provide a better understanding of the action of targeted therapies to move towards personalized medicine by an experimental and applied approach using either cells (stem cells, cells "on") or targeted drugs at histological or molecular level. This 3-Days courses also consist of scientific article analysis sessions usually charged to students in pairs. This education is supposed to renew annually at the same time.