1983-1984 Research Technician, G. D. Searle, High Wycombe, England.
Summer 1985 Research Assistant, G. D. Searle, High Wycombe, England.
Summer 1986 Cadre de Recherche, Laboratoire Roger Bellon, Monts, France.
Summer 1987 Temporary Staff Scientist, Immunex Corporation, Seattle, U.S.A.
1988-1992 Graduate Student:
1988-1990 MRC Laboratory of Molecular Biology, Cambridge, England.
1990-1992 European Molecular Biology Laboratory, Heidelberg, Germany.
Autumn 1992 Sloan-Kettering Center, New York, U.S.A.
1993-1997 Postdoctoral Fellow, McGill University, Montreal, Canada.
1997 Postdoctoral Fellow, CIML, Marseille, France.
1998 Permanent INSERM position (CR1).
1999 Junior group leader, CIML, Marseille, France.
2001 Group leader, CIML, Marseille, France.
2002 Research Director (DR2), INSERM.
2004-2006 Director Marseille-Nice Genopole
2006-2010 Associate Professor at the Université de la Méditerranée
2007- Research Director (DR1), INSERM.
01/2008-07/2008 Visiting Professor, Dept. Biochemistry, University Oxford, UK.
2012- Deputy director, CIML
Our current work aims to (i) identify all the host genes that intervene in the response of C. elegans to fungal infection; (ii) characterise protein complexes involved in signalling networks; (iii) study the intracellular dynamics of protein complexes; (iv) relate these elements to the physiology of the whole organism.
The combined results promise insights into how C. elegans attempts to counter infection. This fundamental knowledge will serve as a paradigm for the epithelial immune defences that counter fungal infection.