Training: Medical studies, Clermont-Ferrand University, 1974-1981 - Medical resident, Endocrinology-Diabetology, Nancy University Hospital, 1980-1983 - Researcher in training, Diabetes Epidemiology, Inserm-U21, Villejuif, 1984-1986 - Lecturer/hospital assistant, Paris 5 and 6 Universities and Broussais and Cochin hospitals, 1987-1988
Tenured researcher, Inserm (French National Institute of Health and Medical Research), since 1989
Present position: IRD (French Institute of Research for Development) - Located at NESC-CPqAM-Fiocruz (Department of Community Health, Aggeu Magalhães Research Centre, Oswaldo Cruz Foundation), Recife, Brazil, since March 2010
Metabolic syndrome as a risk factor for type 2 diabetes and its cardiovascular complications. Past noteworthy contributions: Analyses of the Paris Prospective Study relating plasma insulin to higher risk of ischemic heart disease - Coordination and conduction of the BIGPRO trial, first attempt to test, vs. placebo, an insulin sensitising agent, metformin, for correcting metabolic abnormalities in upper-body obese, non-diabetic subjects - Analyses of the CALDIA Study (DIAbetes in New-CALedonia) showing unusual presentation of the metabolic syndrome in Polynesians.
Evaluation of health services for management of diabetes and other nutrition-related chronic diseases. Past contribution: Evaluation of pilot experiences of organized care and education for type 2 diabetic patients in the Languedoc-Roussillon region. Present research project: Management of hypertension and type 2 diabetes in primary care setting in Brazil, as a possible model for other emerging and developing countries.