CV Science

Archana Singh-Manoux PhD, HDR Epidemiology

Course and current status

EMPLOYMENT

• Research Professor (DR1), INSERM
• Honorary Professor, University College London

HONOURS & AWARDS

• 2018: Prix Coups d'élan, Fondation Bettencourt Schueller
• 2015: Prix Recherche Inserm
• 2010: Member, Academia Europaea, The Academy of Europe
• 2005: Chair of Excellence Award: French Ministry of Research
• 2005: ERC Starting Grant

H-index: 94 (Web of Science), 129 (Google Scholar)

Top 1% Highly Cited Researcher 2017, 2018, 2019, 2020, 2021, 2022, 2023

10 KEY PUBLICATIONS (out of a total >400)

1. Barbiellini Amidei C, Fayosse A, Dumurgier J, Machado-Fragua MD, Tabak AG, van Sloten T, Kivimäki M, Dugravot A, Sabia S, Singh-Manoux A. Association Between Age at Diabetes Onset and Subsequent Risk of Dementia. JAMA. 2021; 325(16):1640-1649. 
2. Sabia S, Fayosse A, Dumurgier J, van Hees VT, Paquet C, Sommerlad A, Kivimäki M, Dugravot A, Singh-Manoux A. Association of sleep duration in middle and old age with incidence of dementia. Nat Commun. 2021; 12(1):2289. 
3. Dugravot A, Fayosse A, Dumurgier J, Bouillon K, Rayana TB, Schnitzler A, Kivimaki M, Sabia S, Singh-Manoux A. Social inequalities in multimorbidity, frailty, disability, and transitions to mortality: a 24-year follow-up of the Whitehall II cohort study. Lancet Public Health. 2020 Jan;5(1):e42-e50.
4. Sabia S, Fayosse A, Dumurgier J, Schnitzler A, Empana JP, Ebmeier KP, Dugravot A, Kivimäki M, Singh-Manoux A. Association of ideal cardiovascular health at age 50 with incidence of dementia: 25 year follow-up of Whitehall II cohort study. BMJ. 2019 Aug 7;366:l4414.
5. Singh-Manoux A, Fayosse A, Sabia S, Tabak A, Shipley M, Dugravot A, Kivimäki M. Clinical, socioeconomic, and behavioural factors at age 50 years and risk of cardiometabolic multimorbidity and mortality: A cohort study. PLoS Med. 2018; 15(5):e1002571. doi: 10.1371/journal.pmed.1002571
6. Abell JG, Kivimäki M, Dugravot A, Tabak AG, Fayosse A, Shipley M, Sabia S, Singh-Manoux A. Association between systolic blood pressure and dementia in the Whitehall II cohort study: role of age, duration, and threshold used to define hypertension. Eur Heart J. 2018;39(33):3119-3125.
7. Singh-Manoux A, Dugravot A, Shipley M, Brunner EJ, Elbaz A, Sabia S, Kivimaki M. Obesity trajectories and risk of dementia: 28 years of follow-up in the Whitehall II Study.  Alzheimers Dement. 2018; 14(2): 178-186.
8. Singh-Manoux A, Dugravot A, Fournier A, Abell J, Ebmeier K, Kivimäki M, Sabia S. Trajectories of Depressive Symptoms Before Diagnosis of Dementia: A 28-Year Follow-up Study. JAMA Psychiatry. 2017; 74: 712-718.
9. Singh-Manoux A, Fayosse A, Sabia S, Canonico M, Bobak M, Elbaz A, Kivimäki M, Dugravot A. Atrial fibrillation as a risk factor for cognitive decline and dementia. Eur Heart J. 2017;38(34):2612-2618.
10. Rusmaully J, Dugravot A, Moatti JP, Marmot MG, Elbaz A, Kivimaki M, Sabia S, Singh-Manoux A. Contribution of cognitive performance and cognitive decline to associations between socioeconomic factors and dementia: A cohort study. PLoS Med. 2017; 14(6):e1002334.

RESEARCH GRANTS (a selection)

• 2019-2024 Principal Investigator R01AG062553, National Institute on Aging, NIH
• 2018-2023 Principal Investigator R01AG056477, National Institute on Aging, NIH
• 2018-2023 Co-Investigator MR/R024227, Medical Research Council, MRC
• 2019-2022 Co-Investigator MR/S011676, Medical Research Council, MRC
• 2017-2019 Principal Investigator R56AG056477, National Institute on Aging, NIH
• 2017-2021 Co-Investigator RG/16/11/32334, British Heart Foundation

Scientific summary

Epidemiology of Ageing and Neurodegenerative diseases (Team EpiAgeing, CRESS), Inserm U1153, Université de Paris

https://twitter.com/epiAgeing

Whitehall II study, University College London, http://www.ucl.ac.uk/whitehallII

My research is on the determinants of cognitive decline and dementia with a focus on socioeconomic, occupational, psychosocial, behavioural and biological factors. A second aspect of my work is on the social determinants of health at older ages in order to understand the mechanisms underlying inequalities in health.