CV Science

Archana Singh-Manoux PhD, HDR Epidemiology

Course and current status

EMPLOYMENT

• Research Professor (DRCE), INSERM
• Honorary Professor, University College London

HONOURS & AWARDS

• 2018: Prix Coups d'élan, Fondation Bettencourt Schueller
• 2015: Prix Recherche Inserm
• 2010: Member, Academia Europaea, The Academy of Europe
• 2005: Chair of Excellence Award: French Ministry of Research
• 2005: ERC Starting Grant

H-index: 104 (Web of Science), 138 (Google Scholar)

Top 1% Highly Cited Researcher 2017, 2018, 2019, 2020, 2021, 2022, 2023, 2024, 2025

10 KEY PUBLICATIONS (out of a total >400)

1. Machado-Fragua MD, Fayosse A, Dumurgier J, Kivimaki M, Ben Hassen C, Livingston G, Paquet C, Sabia S, Singh-Manoux A. Association of midlife hearing impairment and hearing aid use with incident dementia: analysis of two UK-based longitudinal cohort studies. Nat Aging. 2025; 5(9):1732-1738.
2. Vidil S, Danilevicz IM, Dugravot A, Fayosse A, Landré B, van Hees V, Chen M, Singh-Manoux A, Sabia S. Circadian rhythm profiles derived from accelerometer measures of the sleep-wake cycle in two cohort studies. Nat Commun. 2025; 16(1):11357. 
3. Livingston G, Huntley J, Liu KY, Costafreda SG, Selbæk G, Alladi S, Ames D, Banerjee S, Burns A, Brayne C, Fox NC, Ferri CP, Gitlin LN, Howard R, Kales HC, Kivimäki M, Larson EB, Nakasujja N, Rockwood K, Samus Q, Shirai K, Singh-Manoux A, Schneider LS, Walsh S, Yao Y, Sommerlad A, Mukadam N. Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission. Lancet. 2024 Aug 10;404(10452):572-628.
4. van der Heide FCT, Valeri L, Dugravot A, Danilevicz I, Landre B, Kivimaki M, Sabia S, Singh-Manoux A. Role of cardiovascular health factors in mediating social inequalities in the incidence of dementia in the UK: two prospective, population-based cohort studies. EClinicalMedicine. 2024; 70:102539. doi: 10.1016/j.eclinm.2024.102539.
5. van Gennip ACE, van Sloten TT, Fayosse A, Sabia S, Singh-Manoux A. Age at cardiovascular disease onset, dementia risk, and the role of lifestyle factors. Alzheimers Dement. 2024 Mar;20(3):1693-1702. 
6. Hassen CB, Machado-Fragua MD, Landré B, Fayosse A, Dumurgier J, Kivimaki M, Sabia S, Singh-Manoux A. Change in lipids before onset of dementia, coronary heart disease, and mortality: A 28-year follow-up Whitehall II prospective cohort study. Alzheimers Dement. 2023; 19(12):5518-5530. 
7. Barbiellini Amidei C, Fayosse A, Dumurgier J, Machado-Fragua MD, Tabak AG, van Sloten T, Kivimäki M, Dugravot A, Sabia S, Singh-Manoux A. Association Between Age at Diabetes Onset and Subsequent Risk of Dementia. JAMA. 2021; 325(16):1640-1649. 
8. Sabia S, Fayosse A, Dumurgier J, van Hees VT, Paquet C, Sommerlad A, Kivimäki M, Dugravot A, Singh-Manoux A. Association of sleep duration in middle and old age with incidence of dementia. Nat Commun. 2021; 12(1):2289. 
9. Dugravot A, Fayosse A, Dumurgier J, Bouillon K, Rayana TB, Schnitzler A, Kivimaki M, Sabia S, Singh-Manoux A. Social inequalities in multimorbidity, frailty, disability, and transitions to mortality: a 24-year follow-up of the Whitehall II cohort study. Lancet Public Health. 2020 Jan;5(1):e42-e50.
10. Sabia S, Fayosse A, Dumurgier J, Schnitzler A, Empana JP, Ebmeier KP, Dugravot A, Kivimäki M, Singh-Manoux A. Association of ideal cardiovascular health at age 50 with incidence of dementia: 25 year follow-up of Whitehall II cohort study. BMJ. 2019 Aug 7;366:l4414.

RESEARCH GRANTS (a selection)

2024-2028 Principal Investigator France 2030 ANR-23-PAVH-0006
2019-2024 Principal Investigator R01AG062553, National Institute on Aging, NIH
2018-2023 Principal Investigator R01AG056477, National Institute on Aging, NIH
2018-2023 Co-Investigator MR/R024227, Medical Research Council, MRC
2019-2022 Co-Investigator MR/S011676, Medical Research Council, MRC
2017-2019 Principal Investigator R56AG056477, National Institute on Aging, NIH
2017-2021 Co-Investigator RG/16/11/32334, British Heart Foundation

Scientific summary

Epidemiology of Ageing and Neurodegenerative diseases (Team EpiAgeing, CRESS), Inserm U1153, Université Paris Cité

https://cress-umr1153.fr/en/teams/epiageing-en/

Whitehall II study, University College London, http://www.ucl.ac.uk/whitehallII

My research is on the determinants of cognitive decline and dementia with a focus on socioeconomic, occupational, psychosocial, behavioural and biological factors. A second aspect of my work is on the social determinants of health at older ages in order to understand the mechanisms underlying inequalities in health.