CV Science

Jean-Bernard Manent PhD Neurosciences

Course and current status

Position title

INSERM Research Director (DR2 INSERM, permanent position)
Habilitation à diriger des recherches (HDR)

Laboratory: INMED / INSERM U1249 (Marseille, France)

http://orcid.org/0000-0002-2436-8593

Positions and Employment

2025- INSERM Research Director (DR2 INSERM), INSERM U1249, Marseille (France)
2017-2025 INSERM Research Scientist (CRCN INSERM), INSERM U1249, Marseille (France)
2013-2017 INSERM Research Scientist (CR1 INSERM), INSERM U901, Marseille (France)
2009-2012 INSERM Research Scientist (CR2 INSERM), INSERM U901, Marseille (France)
2008-2009 Postdoctoral fellow, INSERM U901, Marseille (France)
2006-2008 Postdoctoral fellow, Department of Physiology & Neurobiology, University of Connecticut (USA)
2005-2006 PhD student, LFCE Fellow, French league against epilepsy, Aix-Marseille University (France)
2002-2005 PhD student, MRT Fellow, Ministry for Research and Technology, Aix-Marseille University (France)
2002-2005 Lecturer, Aix-Marseille University (France)

Education/Training

04/2016     Habilitation à diriger des recherches, Aix-Marseille University (France)        
09/2009     Postdoctoral fellow, INSERM U901 (France)
09/2008     Postdoctoral fellow, University of Connecticut (USA)
06/2006     PhD Neurosciences, Aix-Marseille University (France)
07/2001     MSc Cellular and molecular Neurobiology, Aix-Marseille University (France)

Scientific summary

I lead a research group called 'Altered Cortical Circuits in Malformations of Cortical Development' at INMED (Marseille, France), which is a mixed structure of Inserm (the French government agency for Health and Medical Research), and the University of Aix-Marseille. INMED is one of the largest neuroscience research centres in France, dedicated to studying brain development and plasticity, as well as related neurological pathologies. 

Research in my group focuses on neurodevelopmental disorders and epileptogenic cortical malformations, on the mechanisms responsible for seizure initiation and propagation, and their consequences for cortical function in preclinical rodent models. My expertise lies in generating and morphofunctionally investigating of clinically relevant rodent models of cortical malformations, particularly grey matter heterotopia, and developing tools to manipulate the excitability of cortical circuits.