CV Science

Martin DUTERTRE PhD, Biochemistry and Molecular Biology

Course and current status

1991 : B.Sc. in Cell Biology and Genetics, University of Paris 6, France

1998 : Ph.D. in Biochemistry and Molecular Biology, University of Paris 11, France. Laboratory: INSERM U493 (directors : N. Josso and J.Y. Picard), Ecole Normale Supérieure, Dept of Biology, Paris, France.

1998-2003: Postdoc, team of Carolyn L. Smith, Dept of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, USA.

2003-2005 : Postdoc, team of D. Auboeuf, INSERM U685, Institut Universitaire d’Hématologie, Hôpital Saint Louis, Paris, France.

2005-2013: INSERM researcher (CR1/assistant professor since 2010) in the lab of D. Auboeuf, which was part of INSERM U685 (Hôpital St Louis, Paris, France, 2005-2009) and then of INSERM U1052 (Centre Léon Bérard, Lyon, France, 2009-2013).

2009 : "Habilitation à Diriger des Recherches" (University of Paris 7).

Since Sept. 2013: INSERM researcher (CR1/assistant professor) in the lab of S. Vagner, which is part of UMR 3348 CNRS (Institut Curie, Orsay, France).

Scientific summary

Genomic analyses revealed that the majority of human genes generate alternative transcripts (often encoding protein isoforms) through alternative splicing, alternative polyadenylation and alternative promoters. Since 2003, my primary research intererest has been on the role of alternative transcripts and their regulation by RNA-binding proteins, in cancer development and therapy. I recently contributed to the genome-wide analysis of mRNA isoforms regulation in breast cancer metastasis and in response to estrogen and genotoxic chemotherapeutic drugs.