Jean-Marie Zajac - CV - Ph.D. molecular and cellular biology

E-mail :[email]
Phone : +33 5 61 17 59 11
Location : Toulouse, France

Scientific topics

Neuroscience & Behavior
Pharmacology & Toxicology

Keywords

Neurosciences
Biology

ITMO

Last update 2011-09-01 11:02:17.856

Jean-Marie Zajac Ph.D. molecular and cellular biology

Course and current status

Ph.D. molecular and cellular biology , 1979

Doctorat d'Etat ès Sciences Naturelles, P. et M. Curie University, Paris, 1989

Professional experience

1983 Senior Scientist CNRS, Laboratoire Pharmacochimie Moléculaire INSERM, CNRS, Paris

1989 Laboratoire de Pharmacologie et de Toxicologie Fondamentales, UPR CNRS, Toulouse

1994-1995 Sanofi-Recherche

1996 Institut de pharmacologie et de Biologie Structurale, UPR 9062 CNRS, Toulouse

________Current Position

Director of Research, CNRS, team leader, Institut de pharmacologie et de Biologie Structurale, Toulouse

Scientific summary

Molecular and functional pharmacology of neuropeptide receptors

Our team is devoted to the biochemical, cellular and pharmacological characterization of Neuropeptide FF (NPFF, FLFQPQRFamide), a neuromodulator of the central nervous system, which has been identified as an anti-opioid peptide. Several pharmacological data suggest that NPFF plays an important role in pain modulation and acts mainly through the regulation of the opioid system. The elucidation of the mechanisms underlying such effects is essential to our understanding of pain perception and opiate addiction.