1989 - 1993 PhD student at KU Leuven, Dept of Biochemistry (Belgium)
1993 - 1995 Postdoc at Imperial Cancer Research Fund, London, UK (currently CRUK), supported by Longterm EMBO Fellowship
1995 - 2004 Postdoc at KU Leuven, Dept of Cellular & Molecular Medicine, supported by FWO postdoctoral fellowship (FWO = Research Foundation Flanders)
2004 - present: Professor of Cellular & Molecular Medicine, KU Leuven, Belgium
2014- present: Coordinator of Translational Cancer Research, KU Leuven Cancer Institute (LKI), Leuven, Belgium
My research focuses on the role of reversible protein phosphorylation in health and disease, with a particular focus on cancer. Within this area, my focus is on the Protein Kinase D family of protein kinases, of which PKD1 has a cancer suppressing action, whereas PKD2/3 are rather cancer promoting. One of our aims is to get a mechanistic understanding of these differences. A second research line is dedicated to the development of allosteric protein kinase inhibitors that specifically target PKD2.