POSITION
2023 CNRS Senior Researcher (1st class, DR1) - CNRS UMR6302
ICMUB, Dijon, France.
2017 CNRS Senior Researcher (2nd class, DR2) - CNRS UMR6302
ICMUB, Dijon, France.
2009 CNRS Research fellow (1st class, CR1) - CNRS UMR6302
ICMUB, Dijon, France. Lab. of Pr. Franck Denat.
2007 CNRS Research fellow (2nd class, CR2) - CNRS UMR176
Institut Curie, Orsay, France. Lab. of Dr. Marie-Paule Teulade-Fichou.
2005 CNRS Research fellow (2nd class, CR2) - CNRS UPR282
Collège de France, Paris, France. Lab. of Pr. Jean-Marie Lehn.
EDUCATION
2011 Accreditation to supervise research (Habilitation)
ICMUB, CNRS UMR6302, Dijon, France.
2004 Post-doctoral fellow CNRS / Sanofi-Aventis grant - CNRS UPR282
Collège de France, Paris, France. Lab. of Prof. Jean-Marie Lehn, under the supervision of Dr. Marie-Paule Teulade-Fichou & Dr. Patrick Mailliet.
2002 Post-doctoral fellow PharmaLEADS grant
Université Paris Descartes, Paris, France. Lab. of Prof. Bernard P. Roques.
1998 Ph.D. in Organic Chemistry
Université Sciences II de Genève, Geneva, Switzerland. Lab. of Prof. Jérôme Lacour
After a Ph.D in supramolecular chemistry in Geneva (CH), and two post-docs in medicinal chemistry and chemical biology in Paris (FR), I was awarded a position of CNRS researcher in 2005 in the laboratory of Prof. Jean-Marie Lehn (College de France, Paris) under the supervision of Dr. Marie-Paule Teulade-Fichou. Then, I moved with her to the Institut Curie (Orsay, France) from 2007 to 2009, before taking the responsibility of my own research group GATTACA (for Group “nucleic Acids’ Therapeutic & Technological Applications": Chemistry & bio-Analysis) at the Institute of molecular chemistry (ICMUB) in Dijon.
My research is focused on the use of alternative nucleic acid structures (DNA and RNA) as targets for innovative therapies in two areas, cancers and neuropathologies. I published >120 articles (>6900 citations, H-index: 42) in high-impact factors journals (Nat. Commun., Nat. Rev. Chem., JACS, etc.) along with 2 patents (one licensed). My research is supported by various funding agencies including the ANR (e.g., DEMENTIA 2017, InJUNCTION 2022), ITMO Cancer (ANASTOMOSIS 2019), the EU (SEQUENTIA 2019), I-SITE BFC (ANASTASIA 2021), the NIH (G4-in-NVU 2019) and Ligue contre le cancer (OS pediatric 2023).