Marion Ouidir Environmental epidemiologist, PhD
Course and current status
Researcher, INSERM U1209, Intsitute for Advanced Biosciences, Team Environmental Epidemiology Applied to Development and Respiratory Health
EDUCATION
2017 PhD in Environmental Epidemiology, University Grenoble Alpes, Grenoble, France.
2014 University Diploma in pedagogy and teaching in health, University Joseph Fourier, Grenoble, France.
2013 Master’s degree (MSc year 2) Research Engineering for Health and Medicines, University Joseph Fourier, Grenoble, France.
2012 MSc (year 1) Public health and Environment, School of Public Health, University of Lorraine, Nancy, France.
2010 Midwifery diploma, University Joseph Fourier, Grenoble, France.
Scientific summary
1. Ouidir M, Jedynak P, Rolland M, Lyon-Caen S, Thomsen C, Sakhi AK, Sabaredzovic A, Bayat S, Slama R, Philippat C. Analyzing the impact of phthalate and DINCH exposure on fetal growth in a cohort with repeated urine collection. Environ Int. 2024 Apr;186:108584.
2. Ouidir M, Cissé AH, Botton J, Lyon-Caen S, Thomsen S, Sakhi AK, Sabaredzovic A, Bayat S, Slama R, Heude B, Philippat C. Fetal and Infancy Exposure to Phenols, Parabens, and Phthalates and Anthropometric Measurements up to 36 Months, in the Longitudinal SEPAGES Cohort. Environ Health Perspect. 2024 May;132(5):57002.
3. Li L-J, Du R, Ouidir M, Lu R, Chen Z, Weir N, Tsai M, Albert P, Zhang C. Early Pregnancy Maternal Plasma Phospholipid Saturated Fatty Acids and Fetal Growth Trajectories: the NICHD Fetal-Growth Cohort. Nutrients. 2023;15(15):3287.
4. Sevens DR, Yeung E, Hinkle SN, Grobman W, Williams A, Ouidir M, Kumar R, Lipsky LM, Rohn MCH, Kanner J, Sherman S, Chen Z, Mendola P. Maternal asthma in relation to infant size and body composition. JACI Global. 2023;2(3):100122.
5. Borlaza LJS, Uzu G, Ouidir M, Lyon-Caen S, Marsal A, Weber S, Siroux V, Lepeule J, Boudier A, Jaffrezo JL, Slama R. Personal exposure to PM2.5 oxidative potential and its association to birth outcomes. Journal of Exposure Science and Environmental Epidemiology. 2023;33(3):416-426.
6. Ouidir M, Chatterjee S, Wu J, Tekola-Ayele F. Genomic study of early pregnancy maternal lipid traits revealed four known adult lipid loci. Journal of Clinical Lipidology. 2023;17(1):168-180.
7. Zhao SK, Yeung EH, Ouidir M, Hinkle S, Grantz KL, Mitro SD, Stevens DR, Chatterjee S, Tekola-Ayele F, Zhang C. Recreational physical activity before and during pregnancy and placental DNA methylation - an epigenome-wide association study. American Journal of Clinical Nutrition. 2022;116(4):1168-1183.
8. Chatterjee S, Zeng X, Ouidir M, Tesfaye M, Zhang C, Tekola-Ayele F. Sex-specific placental gene expression signatures of small for gestational age at birth. Placenta. 2022;121/82-90.
9. Tekola-Ayele F, Zeng X, Chatterjee S, Ouidir M, Lesseur C, Hao K, Chen J, Tesfaye M, Marsit CJ, Workalemahu T, Wapner R. Multi-omics integration in placenta identifies candidate functional genes for birthweight. Nature Communications.2022;13:2384
10. Ouidir M, Zeng X, Chatterjee S, Zhang C, Tekola-Ayele F. Ancestry-matched and cross-ancestry genetic risk scores of type 2 diabetes in pregnant women and fetal growth - a study in an ancestrally diverse cohort. Diabetes. 2022;71:340–349.
11. Ouidir M, Chatterjee S, Mendola P, Zhang C, Grantz K.L, Tekola-Ayele F. Placental gene co-expression network reveals inflammation response enrichment to early maternal dyslipidemia. Frontiers in Genetics. 2021;12(1946):681095.
12. Kanner J, Stevens D, Nobles CJ, Rohn MCH, Ha S, Mannisto T, Ouidir M, Mendola P. Risk of cardiovascular events during labor and delivery associated with acute ambient temperature changes. The Journal of Climate Change and Health. 2021;3:10060.
13. Ouidir M, Tekola-Ayele F, Canty T, Grantz KL, Sciscione A, Tong D, Jones RR, Sundaram R, Williams A, Stevens D, Mendola P. Acute ambient air pollution exposure and placental Doppler results in the NICHD Fetal Growth Studies – Singleton Cohort. Environmental Research. 2021;202:111728.
14. Chatterjee S, Ouidir M, Tekola-Ayele F. Genetic and in-utero environmental contributions to DNA methylation variation in placenta. Human Molecular Genetics. 2021;30(21)1968-1976.
15. Ouidir M, Seyve E, Rivière E, Bernard J, Cheminat M, Cortinovis J, Ducroz F, Dugay F, Hulin A, Kloog I, Laborie A, Launay L, Malherbe L, Robic P-Y, Schwartz J, Siroux V, Virga J, Zaros C, Charles M-A, Slama R, Lepeule J. Maternal Ambient Exposure to Atmospheric Pollutants during Pregnancy and Offspring Term Birth Weight in the Nationwide ELFE Cohort. International Journal of Environmental Research and Public Health. 2021; 18(11):5806.
16. Williams A, Kanner J, Grantz KL, Ouidir M, Li S, Sherman S, Robledo C, Mendola P. Air pollution exposure and risk of adverse obstetric and neonatal outcomes among women with type 1 diabetes Environmental Research. 2021;197:111152.
17. Tekola-Ayele F, Ouidir M, Shrestha D, Workalemahu T, Rahman ML, Mendola P, Grantz KL, Zhang C, Grewal J, Hinkle S.N, Wu J. Admixture mapping identifies African and Amerindigenous local ancestry loci associated with fetal growth. Human Genetics. 2021;140(7):985-997.
18. Workalemahu T, Rahman M, Ouidir M, Wu J, Zhang C, Tekola-Ayele F. Associations of maternal blood pressure-raising polygenic risk score with fetal weight. Journal of Human Hypertension. 2022;36(1):69-76.
19. Chatterjee S, Ouidir M, Tekola-Ayele F. Pleiotropic genetic influence on birthweight and childhood obesity. Scientific Reports. 2021;11:48.
20. Ha S, Nobles CJ, Kanner J, Sherman S, Cho S-H, Perkins N, Williams A, Grobman W, Biggio J, Subramaniam A, Ouidir M, Chen Z, Mendola P. Air pollution exposure monitoring among pregnant women with and without asthma. International Journal of Environmental Research and Public Health. 2020;17(13):4888.
21. Kanner J, Williams A, Nobles CJ, Ha S, Ouidir M, Sherman S, Mendola P. Ambient temperature and stillbirth: Risks associated with chronic extreme temperature and acute temperature change. Environmental Research. 2020;189:109958
22. Ouidir M, Mendola P, Buck Louis GM, Kannan K, Zhang C, Tekola-Ayele F. Concentrations of persistent organic pollutants in maternal plasma and epigenome-wide placental DNA methylation. Clinical Epigenetics. 2020;12(1):103.
23. Tekola-Ayele F, Zeng X, Ouidir M, Workalemahu T, Zhang C, Delahaye F, Wapner R. DNA methylation analysis identifies loci in placenta associated with birthweight and expression of genes relevant for early development and adult diseases. Clinical Epigenetics. 2020;12(1):78.
24. Tekola-Ayele F, Zhang C, Wu J, Grantz KL, Rahman ML, Shrestha D, Ouidir M, Workalemahu T, Tsai MY. Trans-ethnic meta-analysis of genome-wide association studies identifies maternal ITPR1 as a novel locus influencing fetal growth during sensitive periods in pregnancy. PLOS Genetics. 2020;16(5): e1008747.
25. Ouidir M, Zeng X, Workalemahu T, Shrestha D, Grantz KL, Mendola P, Zhang C, Tekola-Ayele F. Early pregnancy dyslipidemia is associated with placental DNA methylation at loci relevant for cardiometabolic diseases. Epigenomics. 2020;12(11):921-934.
26. Shrestha D, Ouidir M, Workalemahu T, Zeng X, Tekola-Ayele F. Placental DNA methylation changes associated with maternal pre-pregnancy BMI and gestational weight gain. International Journal of Obesity. 2020;44(6):1406-1416.
27. Workalemahu T, Ouidir M, Shrestha D, Wu J, Grantz KL, Tekola-Ayele F. Differential DNA methylation in placenta associated with maternal blood pressure during pregnancy. Hypertension. 2020;75(4):1117-1124.
28. Ouidir M, Buck Louis GM, Kanner J, Grantz KL, Zhang C, Sundaram R, Rahman ML, Lee S, Kannan K, Tekola-Ayele F, Mendola P. Association of maternal exposure to persistent organic pollutants in early pregnancy with fetal growth. JAMA Pediatrics. 2020;174(2):149-161.
29. Ouidir M, Mendola P, Workalemahu T, Grewal J, Grantz KL, Zhang C, Wu J, Tekola-Ayele F. Race/ethnic differences in the associations of maternal lipid trait genetic risk scores with longitudinal fetal growth. Journal of Clinical Lipidology. 2019;13(5):821-831.
30. Nobles CJ, Williams A, Ouidir M, Sherman S, Mendola P. Differential effect of ambient air pollution exposure on risk of gestational hypertension and preeclampsia. Hypertension. 2019;74:384–390.
31. Williams A, Grantz KL, Seeni I, Robledo C, Li S, Ouidir M, Nobles C, Mendola P. Obstetric and neonatal complications among women with autoimmune disease. Journal of Autoimmunity. 2019;103:102287
32. Tekola-Ayele F, Lee A, Workalemahu T, Zhang W, Shrestha D, Amare AT, Ouidir M. Genetic pleiotropy in birthweight and adult cardiometabolic diseases: implications for genomic medicine. Scientific Reports. 2019;9(1):4076.
33. Nobles C, Grantz KL, Liu D, Williams A, Ouidir M, Seeni I, Sherman S, Mendola P. Ambient air pollution and fetal growth restriction: physician diagnosis of fetal growth restriction versus population-based small-for-gestational age. Science of the Total Environment. 2019;650(Pt 2):2641-2647.
34. Ouidir M, Lepeule J, Siroux V, Malherbe L, Meleux F, Launay L, Zaros C, Cheminat M, Charles MA, Slama R. Is atmospheric pollution exposure during pregnancy associated with individual and contextual characteristics? A nationwide study in France. Journal of Epidemiology and Community Health. 2017;71:1026-36.
35. Ouidir M, Giorgis-Allemand L, Lyon-Caen S, Morelli X, Cracowski C, Pontet S, Pin I, Lepeule J, Siroux V, Slama R. Estimation of exposure to atmospheric pollutants during pregnancy integrating space-time activity and indoor air levels: does it make a difference? Environment International. 2015;84:161–73.
