CV Science

Tiphaine Le Roy PhD Biology

Course and current status

Since Jan. 2023  UMRS 1269 NutriOmics. Sorbonne Université INSERM, Paris, France.

Permanent Scientist - Subject: Study of the impact of the microbiota in obesity and type 2   diabetes with a focus on the small intestine microbiota.

Jan. 2020  to Dec. 2022. UMRS 1269 NutriOmics. Sorbonne Université INSERM, Paris, France. Prof K. Clément.

  Postdoctoral fellow - Subject: Identification of two bacterial species associated with type   2 diabetes remission after bariatric surgery and study of their mechanisms of action.

Nov. 2016  to Nov. 2019. Université catholique de Louvain. Louvain Drug Research Institute, Brussels, Belgium. Metabolism and Nutrition team – Prof P. Cani.

 Postdoctoral fellow - Subject: Isolation and characterization of potential new probiotics   isolated from the human gut.

Jan. 2016  to Oct. 2016. UMR 1166 ICAN (Institute of Cardiometabolism and Nutrition), Sorbonne Université, INSERM, Paris, France – Nutriomics team – Prof K. Clément.

  Postdoctoral fellow - Subject: Development and validation of a model of intestinal   microbiota transfer based on the use of conventionally raised mice.

Sept. 2012 to Dec. 2015. UMR 1166 ICAN (Institute of Cardiometabolism and Nutrition), Sorbonne Université, INSERM, Paris, France – Biologie integrative de l’Atheroschlérose – Dr P. Lesnik.

Postdoctoral fellow - Subject: Impact of gut microbiota on host cholesterol metabolism.

Oct. 2008  to Feb. 2012. INRA – Micalis Institute, Jouy en Josas, France – Amipem team – Dr P. Gérard.

Graduate Student – Subject: Involvment of gut microbiota in diet-induced non-alcoholic fatty liver disease, study on a mouse  model.

Scientific summary

I am a permanent scientist at INSERM (Institut National de la Santé et de la Recherche Médicale) in NutriOmics team (https://www.nutriomique.org/). During my PhD, that I obtained in 2012, I focussed her research on the contribution of the intestinal microbiota to the development of non-alcoholic fatty liver disease. Then, I moved to a post-doctoral position at the Institute of Cardiometabolism and Nutrition, where I studied the regulation of host cholesterol metabolism by the gut microbiota. After that, I performed a second post-doctorate at UCLouvain (Belgium), during which I isolated and characterized new bacterial species from the human microbiota, such as Dysosmobacter welbionis, and studied their impact on host metabolism. On my return to France in 2020, I joined NutriOmics team at La Pitié Salpêtrière Hospital in Paris. My research interests include isolation of new microbes from the human small intestine microbiota, the study of potential new benefical microbes and the study of host-microbiota interactions using jejunal organoids.