Research positions
Since 2014: Team leader, IGBMC: Chromatin stability and DNA mobility- Integrated Structural Biology Department
2008-2018: Marie Curie International Reintegration Grant fellow -IGBMC, Strasbourg, France
Since 2009 : Associate Professor, IGBMC-Strasbourg University Hospitals (MCU-PH class 1)
2003-2008: Postdoctoral fellow, The Rockefeller University, New York, USA
Structural studies of Bacterial RNA polymerase complexes
2000-2003: Postdoctoral associate, IGBMC, Strasbourg France
Thermus DNA topoisomerases structural studies
Academic responsabilities
Since 2021: Deputy Vice-President for Research, in charge of Life Sciences and Health, Strasbourg University
2017-2020: Deputy Vice-President for Research, in charge of Interdisciplinarity, Strasbourg University
Since 2016: President of the French national network of MD-PhD programs
Since 2013: Coordinator of Strasbourg University MD-PhD programme, Strasbourg Uiversity Initiative of Excellence
Training and diplomas
2011 : Habilitation for Research Direction (HDR), Strasbourg University
1999: PhD Structural Biology, Strasbourg University, France
Structural studies of human transcription/repair factors- IGBMC
1995: DEA in Biological NMR and Crystallography, Strasbourg University, France
1994: Chemical Engineer degree, EHICS Strasbourg France
V. Lamour has joined the IGBMC Integrative Structural Biology Department in 2008 through a Marie Curie International Reintegration grant (FP7). Her research project is aiming at the functional and structural studies of human DNA topoisomerase 2 (Top2) complexes targeted by therapeutic compounds used in cancer treatment. The goal of this study is to identify and study the architecture of Top2-associated complexes targeted by anti-cancer drugs through a combination of biochemical and structural approaches.Since 2014, V. Lamour is co-directing the IGBMC team "Chromatin stability and DNA mobility" with M. Ruff who focuses on HIV integration complexes. The team uses a combination of structural techniques such as in solution biophysical methods, cryo-electron microscopy, x-ray crystallography with biochemistry and proteomic techniques to address biomedical relevant questions.
The Integrative Structural Biology Department offers state-of-the-art structural biology equipments and access to scientific platforms within the IGBMC. The department is one of the two French nodes for the european infrastructure in structural Biology INSTRUCT-ERIC and coordinator of the french infrastructure FRISBI for structural biology.
V. Lamour is the coordinator of Strasbourg University MD-PhD Idex program since 2013 and Deputy Vice-President for Research of Strasbourg University, in charge of Life Sciences and health since March 2021.
The Topo project members
Valerie Lamour, associate professor (MCU-PH, coordinator)
Viola Mazzoleni, assistant professor (MCU)
Philippe Ramain, researcher (DR CNRS)
Robert Drillien, researcher (DR Inserm émérite)
Naveen Murugasamy, PhD student
Brian Lopez Duran, PhD student
Vita Vidmar, PhD student (co-direction with A. Weixlbaumer's team, IGBMC)
Education
Nina Prats-Torne, MD-PhD administrative assistant
Former Members of the Topo project:
Marlène Vayssières, Postdoc 2020-2022
Léa Haas, Master 2 student and research engineer 2020-2021
Loup Petit, ESBS engineering school student 2021
Lucas Dubs, Master 1 student 2021
Fabien Flieg, Licence 3 student 2020
Christophe Lotz, PhD student 2017-2020
Arnaud Vanden Broeck, PhD student 2015-2018
Claire Bedez, PhD student 2011-2015
Morgane Gilg, Master student 2015
Claire Batisse, research engineer 2012-2014
Pélagie Fichter, Master student 2013
Geoffrey Gourinchas, Master student 2013
Julie Papillon, PhD student 2008-2012
Albin Simoni, research engineer 2010
The HIV project members :
Marc Ruff (coordinator)
Julien Batisse (assistant professor)
Rui Zhu (PhD student)
Nicolas Levy (research collaborator)
Robert Drillien (researcher)
Sylvia Eiler (engineer)
Sylvie Duclaud (technician)