CV Science

Patrizia Alberti Master in Physics, University of Milan (Italy); PhD in Biophysics, National Museum of Natural History, Paris (France)

Course and current status

September 1995 - January 1997: Faculty of Pharmacy, University of Strasbourg (France) and Physics Department, University of Milan (Italy) - Structure and dynamics of TetR protein by time-resolved fluorescence spectroscopy and by molecular modelling.

February 1997 - March 1998: Physics Department, University of Milan (Italy) - Fourier transform infrared spectroscopy of biomolecules in aqueous solutions, of intact cells and of pathogen microorganisms.

April 1998 - March 1999: Sistemi Informativi (IBM company), Milan (Italy) - Programmer analyst.

April 1999 - July 2003: Biophysics Laboratory, National Museum of National History, Paris (France) Thermodynamic and kinetic characterisation of non-canonical DNA structures (three- and four-stranded structures) by absorption and fluorescence spectroscopy and by surface plasmon resonance (March 2000-Avril 2003: PhD student).

September 2003 - March 2005: Post-doc, Cisbio, Bagnol sur Cèze (France) - Design of lanthanide-based supramolecular probes for multidetection of molecular processes by time resolved-fluorescence resonance energy transfer (1 patent).

Since April 2005: Assistant professor (Maître de Conférences), National Museum of Natural History, Paris (France); laboratory: CNRS UMR 7196, INSERM U 1154; team: Nucleic Acid Structures, Telomeres and Evolution.

2012-2016: Member of the Inserm Specialized Scientific Committee 1 (CSS1) .

Scientific summary

My main research topic is the characterization of the structure, stability and dynamics of particular nucleic acid sequences, potentially able to fold into non-canonical conformations and potentially involved in genome regulation. I am particularly interested in G-quadruplex structures.