2011- current Head of an INSERM Research Unit (INSERM 1084)
2012-current Inserm Regional Scientific correspondant
2002-current Professor at the University of Poitiers
2016-2018 Vive dean of the faculty of Medecine and Pharmacology
1999-2002 CNRS senior scientist (CR1), Bordeaux II University at INSERM 259 directed by Pr. Michel Le Moal
1995-1999 CNRS junior scientist (CR2) at CNRS UMR 5541 under the supervision of Pr. Bertrand Bloch. Bordeaux-France
1994-1996 Post doctoral researcher at the Howard Hughes Medical Institute, Duke University (Superviser: Pr. M G. Caron). North Carolina-USA. EMBO fellowship
1990-1993 Ph.D student at the Bordeaux II University, CNRS UMR 5541 (Superviser: Pr. B Bloch. Fellowship from the French ministry of research and technology
I obtained my thesis from the University of Bordeaux II (1993) working the expression of neuroactive molecules in the brain with a focus on dopamine neurotransmission. During my PhD, I spent 3 months at the Karolinska Institute-Sweden where I participated to the cloning and characterization of a novel neurotrophic factor receptor (TrkC). I underwent my 3 years post-doc at Duke University-USA (Marc G. Caron) during which I participated to the characterization of transgenic mice lacking the DAT or the beta-adrenergic receptor kinase-1 gene (1993-1995) with professor Robert Lefkowitz (Nobel Prize in 2012). I was recruited as a CNRS researcher (1995) at Bordeaux before becoming a Professor at the University of Poitiers (2002). From 2006-2010 I was the leader of a CNRS research team working on the physiopathology of disorders associated with the malfunctioning of the dopaminergic system such as Parkinson disease and addiction. In 2012, I founded an Inserm Neuroscience laboratory that I have been leading since.
Throughout my career I have published more than 100 papers on the topic dopamine neurotransmission in journals such as Nature, Science, Nature Neuroscience, PNAS and Neuron. My H factor is 35, several of my papers were commented in faculty 1000 Medicine and faculty 1000 Biology. The 2007 Nature Neurosciences paper was elected Scientific Highlight of the year 2007 by the European Neurosciences Federation.
I have extensive expertise in managing and evaluating research project as attested but my many local, national and international responsibilities.
I was a member of the national committee of the CNRS, Physiology section 25; a member of the Neurosciences INSERM committee for 5 years, was for the last 6 years member of the French Neurosciences Society board and member of the election committee; president and member of HCERES committee in Neurosciences; a scientific expert for (i) the French ministry of research and higher education, (ii) the ANR Era-Net Neuron, (iii) the Neuropole Paris, (iv) the Neurological Foundation-New Zealand, and (v) the Parkisnon’s Disease Society-UK. I am also the head of an international cooperation programm involving several teams with Lebanon and French Ministry of foreign affairs and PICS –CNRS and a member of a GDRI-CNRS for cooperative projects with Morocco. In the last 5 year, I have been a jury member for over 30 thesis and HDR diplomas including five international ones and jury member for the recruitment of several professors and assistant professors. At the local level, I was the head of the CPER « handicap and aging » for the Poitou-Charentes Region, vice-dean of faculty of medecine and pharmacology.