CV Science

Angélique Levoye Associate Professor, PhD

Course and current status

EDUCATION

• Sept 2016 : Associate Professor, INSERM U970  « Regenerative Therapies For Cardiac And Vascular Diseases » - Paris Cardiovascular Research Center (PARCC) 

• 2015 : Accreditation to supervise research (HDR), Paris 13 University, France

• 2011-16: Associate Professor, « INSERM-University Chair position » INSERM U1148  « Laboratory of Vascular Translational Science» - Paris 13 University

•  2010-11 : Research assistant in F. Arenzana-Seisdedos ’s laboratory at the Pasteur Institute, Paris, France

• 2006-09 : Post-doctoral fellow in F. Bachelerie‘s team at the Pasteur Institute, Paris, France

• 2002-05 : PhD in molecular pharmacology in R. Jockers ’s team at the Cochin Institute, Paris, France (Paris 11 University)

• 2001-02 : Master degree in cell biology at the Lille 1 University, France

AWARDS AND HONOURS

2011-16 Excellence research chair program INSERM & University

2009-11 Pasteur-Roux-Cantarini Postdoctoral fellowship

ADMINISTRATIVE EXPERIENCE

-2020-24 : Member of National Council of University (CNU) Section 65 (cellular biology)

-2012-16 :member of direction committee of the research group CNRS GDR RCPG-Physio-Med

-Editorial Board; associated editor for Frontiers in Endocrinology, Associated member Faculty of 1000 (2012-15), Journal of leukocyte biology.

Scientific summary

I obtained my PhD in Biochemistry and Molecular Biology from Paris Sud 11 University in 2005. During my PhD in Ralf Jocker’s Team at Cochin Institute in Paris, my work consisted to investigating the functional consequences of melatonin receptors heterodimerization and to searching the function of orphan G-Protein Coupled Receptor (GPCR) GPR50. This work was the first demonstration that orphan GPCR can modulate the function of GPCR with identified ligand and known function. 

In 2006, I jointed the Françoise Bachelerie’s Team at Pasteur Institute in Paris as post-doctoral fellow. During this period, I’m interested to the interactions between the chemokine CXCL12/SDF-1 and it’s receptors CXCR4 and ACKR3/CXCR7 in a physiological and in WHIM syndrome, a rare and inherited chemotactic disorder determined by a pathologic gain of function of CXCR4 in response to CXCL12. 

In 2011, I have a permanent position as associate professor at the University Sorbonne Paris Nord. I worked at INSERM U1148 (Laboratory of Vascular Translational Science) at Bichat hospital in Paris where I investigated the role of High Density Lipids (HDL) receptors in vasculo-protective effects of HDL on Blood-Brain Barrier in ischemic sroke.

Since 2016, I work in the Jean-Sebastien Silvestre ’s Team at Paris Cardiovascular Research Center (PARCC / Georges Pompidou European Hospital), and I interested to the role of CXCL12 isoforms and ACKR3/CXCR7 receptor in post-ischemic remodeling and cardiac regeneration after myocardial infarction by combining genetic approaches in the mouse with a wide range of cell and molecular biology methods.

Bibliometric indicators

https://orcid.org/0000-0002-7125-7327