John DE VOS MD PhD Molecular Biology

Course and current status

Education

1998 - Medical Doctor (Clinical Haematology),  Faculté de Médecine Saint-Antoine, Paris VI

2001 - PhD « Sciences Chimiques et Biologiques pour la Santé », Université Montpellier I

2004 - 2006 : Trained in human embryonic stem cells culture and derivation in Pr Josef Itskovitz-Eldor's laboratory at the Stem cell Research Center, Technion-Israel Institute of Technology (Haifa, Israel) in 2004 and in the Laboratory of Pr. Outi Hovatta, Karolinska Institute, Stockholm, Sweden in 2006.

2008 -  Habilitation à Diriger la Recherche (HDR), University of Montpellier 1

 

Medical and Research positions

2004- Associated Professor, University Hospital Montpellier and University of Montpellier 1

2009-  Director of the Cell Processing Facility, University Hospital Montpellier

2012- Tenured Professor in Histology, University Hospital Montpellier and University of Montpellier 1 

2012- Co-manager of the SAFE-IPS cell reprogramming platform of the IRB, labelled “Infrastructure Nationale de Biologie Santé”

2014- Director of the Department of Cell and Tissue Engineering, Director of Cord Blood Bank

Scientific summary

I was one of the first in France to work with hESC after the bioethics law (Loi de Bioéthique) was modified in 2004, and also among the very first in France to derive hESC lines (HD83, HD90, HD129, HD287 and HD291). In addition, my group obtained more than 10 human iPS cell lines by reprogramming foreskin fibroblasts. After having focused on the determinant of pluripotency by using microarrays and flow cytometry, the group has moved its focus on the genetic stability of pluripotent stem cells and their capacity to differentiate into bronchial epithelium. We are tackling these issues both on hESC and hiPSC.

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