Scientific topics
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Marc-André Mouthon PhD
Course and current status
Since 2003 Senior Researcher at the Laboratory of Radiopathology, UMR967 INSERM_CEA/DSV/iRCM, (Fontenay-aux-Roses, France)
1994-2002 Researcher: « Acute irradiation syndrome and its treatment », Institut de Radioprotection et de Sûreté Nucléaire (Fontenay-aux-Roses, France)
2007 Accreditation to supervise research, University of Paris Sud XI
1993 PhD in Hematopoiesis/Oncology, University of Paris VII
1990 M Sc in Hematopoiesis/Oncology University of Paris VII
Scientific summary
Cranial irradiation, which is a central adjuvant treatment for brain tumours in both paediatric and adult patients, decreases neurogenesis and contributes to cognitive decline. We seek to determine radiation-induced pathophysiological mechanisms directly involving neural stem cells and/or their microenvironment. The aim of my research is to better understand mechanisms controlling adult neurogenesis in normal and pathological situations, an important approach for the development of cellular therapies vis-à-vis diseased nervous system.
