jean-luc morel PhD Neurosciences and Pharmacology/HDR

Course and current status

Since 2001: Permanent senior scientist at Institute of Neurodegenerative Diseases (CNRS UMR 5293), Univ. Bordeaux

Education, training and employment:

2005: Habilitation à Diriger des Recherches (HDR, Université Bordeaux 2)

2001: CR1 Permanent senior scientist poistion CNRS

1998: CR2  Junior scientist position CNRS

1997: PhD Neurosciences and Pharmacology, Univ. Bordeaux 2

1993: DEA  Neurosciences and Pharmacology, Univ. Bordeaux 2

1992: Maîtrise  Physiology, Univ. Nantes

1991: Licence Cellular Biology and Physiology, Univ. Nantes

1990: DEUG Life Sciences - Biochemistry, Univ. Rouen

Scientific expert for academic and industrials entities:

1997,2009: Welcome Trust, UK

2002: Ernst & Young

2007-2010: Conseil Régional de Basse Normandie

2007-2010: Ministry of Culture, Higher Education and Research, Luxembourg

Scientific summary

Our team aims at elucidating the spatio-temporal evolution of memory traces and of their underlying cerebral support during the processes of encoding, storage and retrieval in normal and pathological conditions. Since brain function integrates several intermingled components such as neuronal and vascular networks, short- and long-term plasticity, molecular, cellular and regional interactions, we have grouped together, within the same team, complementary expertise in behavioral testing procedures, functional brain imaging, confocal calcium imaging of cellular activity, electrophysiological recordings of large cerebral assemblies and molecular techniques.

The research project is focusing on unraveling some of the key mechanisms that govern the interactions between neuronal and vascular networks during memory processing in normal and physiological conditions. This first objective will constitute an essential stepping stone in further exploring how neuronal and vascular networks are reorganized and altered in the event of memory dysfunction, whether associated with normal aging or with more severe pathological conditions such as Alzheimer’s disease; vascular pathologies (stroke, hypertension) or under modified gravity levels. Our research projects involve the use of animal models.

Image d’exemple