Nathalie Saint PhD, Biochemistry

Course and current status

EducatioN                      

- University of Montpellier (France) - DU generative medecine, 2012

- University of Rouen (France) – HDR, 2011

- University of Paris VI (France), Ph.D. in biochemistry and biophysics, 1992

- University of Rouen (France), M. Sc. in chemistry, 1988

- University of Rouen (France), B.Sc. in chemistry, 1986

 RESEARCH   

- CNRS Researcher at U1046 INSERM Physiologie et médecine expérimentale du coeur et des muscles, Montpellier (France) (09/2009 - present)

- CNRS Researcher at U5048 CNRS Centre de Biochimie Structurale , Montpellier (France) (10/2001 to 08/2009)

-CNRS Researcher at UMR 6522 CNRS « Polymères, Biopolymères, Membranes », Rouen (France) (10/1998 to 09/2001)

-Postdoctoral scientist at the department of pharmacology of Western australian University, Perth (Australia) (03/1997 to 09/1998)

- Postdoctoral  scientist at the department of microbiology of Basel University, Basel, (Switzerland) (04/1993 to 10/1996)

Scientific summary

Membrane proteins biochemistry and biophysics (ion channel studies at the single channel level in planar lipid bilayers)

Present interests:

Dysfunction of the ryanodine receptor from the sarcoplasmic reticulum  (SR) from contractile cells:

-         In the diaphragm muscle weakness induced by mechanical ventilation

-         In animal models of the Duchenne Muscular Distrophy (DMD)

-         In SR-mitochondria calcium exchanges and SR stress