• E-mail :[email]
  • Phone : 33 4 67 41 52 28
  • Location : Montpellier, France
Last update 2023-04-06 08:24:44.103


Course and current status


 - 2003: Accreditation to supervise research, Faculty of Medicine Montpellier France:

- 1995: PhD Faculty of Science, Tours France

- 1992: BSc Faculty of Science, Tours France



- 2022- : DRCE CNRS

- 2021- : Director Phymedexp (Inserm U1046, UMR CNRS 9214) 

-  2019-2020 : Deputy Director Phymedexp 

- 2017- : Deputy Director FHA Regenhab

- 2017-2020 : Director of the International associated Laboratory with Pr AR Marks (Columbia University New York)

- 2010- : Research Director CNRS in the Inserm U1046 (Dir J Mercier) Montpellier France

-2004-2010 : Associate Scientists for CNRS in the INSERM U637 (Dir. S. Richard) Montpellier France.

-1999-2004 : Associate Scientists for CNRS in the INSERM U390 (Dir. G. Vassort) Montpellier France.

-1998-1999 : Postdoctoral fellow in INSERM U390 (Dir. G. Vassort) Montpellier France.

-1995-1998 : Postdoctoral fellow in the laboratory of Prof M. Schneider, Univ. of Maryland, Baltimore USA.

-1992-1995 : PhD student, Faculty of Sciences, Tours France


Awards and Honors

-2023: Holder of a Silver Medal, CNRS. (

-2014: Schaefer research award, University of Columbia (New York USA).

-2013-2021: Holder of a CNRS excellence recognition (Prime d’excellence Scientifique)

-2010-2013: Holder of a Translational Research Contract with the Montpellier University Hospital.

-2008: President of the organizing committee of the “Printenps de la Cardiologie (annual meeting of the French society of Cardiology).

-2004: Holder of a Bronze Medal, Physiology Department of CNRS.


 Scientific expertise

- Member nominated of the CSS3 Inserm (Physiopatology section, 2022-). 

- Member of the CRBSP Montpellier University Hospital (2022-).

- "Société de Physiologie et Biologie Intégrative" member of the board of directors (2019-) 

-Member elected of the National Scientific committee of the CNRS (Physiology section, 2004-2008, 2012-2021).

-“Groupe de Réflexion et de Recherche sur la Recherche Cardiovascualire“, member of the board of directors (2004-2010).

-Member elected of the National Scientific committee of the CNRS (Physiology section,).

-Member of the technical committee of the Center for Clinical Investigation, Montpellier University Hospital.

-Member elected of the Scientific Committee of the Medical School, University of Montpellier (2006-2010).

Scientific summary

My main scientific interest is focused on excitation-contraction (EC) coupling in cardiac and skeletal muscle both in normal and pathophysiological situation. In this context I have contributed to demonstrate the pathophysiological role of the sarcoplasmic reticulum (SR) calcium channel, ryanodine receptor (RyR). Under pathological stresses, this channel exhibits post-traductional modifications inducing deleterious SR calcium leak. Our current work aimed at determining upstream mechanisms accounting for these post-traductional changes and to identify pharmacological target to prevents RyR defects and restore normal calcium homeostasis and EC coupling .     

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