CV Science

Pascal Colosetti Biomedical engineer (extracellular vesicles expertise)

Course and current status

Professional experience

2016-Today   Research engineer within Inserm U1060-INRAe 1397-CarMeN-Université Lyon 1  (H. Vidal, Lyon, France): expertise in studying extracellular vesicles from different origins (eukaryotes, plants and prokaryotes)

62 publications (February, 2022), 3079 citations, H-Index: 25

Founder and director of the European School for the Study of Extracellular Vesicles (ESSEV, @EV_School_ESSEV) 

2012-2017   Member of the Inserm Scientific Council

2001-2016   Research engineer within Inserm U1065-C3M (P. Auberger, Nice, France): Extracellular vesicles (microvesicles and exosomes) in cancer, chemoresistance and inflammation

1997-2001   Research engineer within Inserm U442 (J.-P. Mauger, Orsay, France): InsP3R expression and regulation during cell polarization

Diplomas and qualifications

2011   International Cancer Technology Transfer fellow at the Krefting Research Centre-Göteborg University, (Prof. J. Lötvall, Sweden) (UICC-ICRETT grant)

2008   Inter-university diploma (DIU) on acquired chromosomal pathologies (Bordeaux, Grenoble, Lille, Lyon, Marseille, Nice and Paris-Sud Universities)

2000   Transgenesis and homologous recombination diploma (Paris 6 University)

1994-1997   Postdoctoral fellow at the Laboratoire de Recherche en Oncologie of the Centre Alexis Vautrin (Nancy, France): Anticancer treatment resistance (Prof. J.-L. Merlin)

1991-1994   Postdoctoral fellow at the Ludwig Institute for Cancer Research (Uppsala, Sweden):  TGF-beta  activation and LTBP expression (Prof. C.-H. Heldin and Prof. K. Miyazono)

1991-1987   PhD in Biomedical Engineering at the Inserm U284 (Nancy University, France): TGF-beta 1 purification, a human platelet derived growth factor (C. Rivat and Prof. J.F. Stoltz)

Scientific summary

After completing my PhD on the TGF-beta 1 purification, a human platelet derived growth factor, at the Inserm U284 in Nancy, I was as a postdoctoral fellow at the Ludwig Institute for Cancer Research in Uppsala on TGF-beta activation and LTBP expression; followed by an other fellowship at the Laboratoire de Recherche en Oncologie (Centre Alexis Vautrin in Nancy) coordinating a cancer treatment resistance project.

I then got a permanent position as research engineer at the Inserm U442 in Orsay to study the InsP3R expression during cell polarization.

I next joined the Inserm U1065-C3M in Nice involved in cell death, differentiation, inflammation and cancer; last years, I developed skills in the characterization of extracellular vesicles (microvesicles, exosomes...) in cancer, chemoresistance and inflammation.

I'm now part of the Inserm U1060-INRAe 1397-CarMeN-Université Lyon 1 in Lyon to study extracellular vesicles in metabolic disorders, founder and director of the European School for the Study of Extracellular Vesicles (ESSEV, @EV_School_ESSEV).