CV Science

Julie Klein PhD Renal pathophysiology, INSERM Researcher

Course and current status

ACTUAL SITUATION Scientist INSERM U1048/Team 12, Toulouse, France

PAST RESEARCH EXPERIENCE

2014 Postdoctoral fellow at the School of Computer Science, University of Manchester, UK 

2013-2014 Postdoctoral fellow at Mosaiques Diagnostics and Therapeutics GmbH, Hannover, Germany

2012-2013 Postdoctoral fellow at the School of Computer Science, University of Manchester, UK

2009-2011 Postdoctoral fellow at INSERM U1048, Toulouse, France

2005-2009 PhD student at INSERM U858, Toulouse, France  

EDUCATION

2005-2009 PhD in Pharmacology and Pathophysiology, Summa cum laude, Université Paul Sabatier, Toulouse, France

2004-2005 Certificate of Advance level Study in Biology and Biotechnologies, Université Paul Sabatier, Toulouse, France

2003-2004 Master in Cellular Biology and Physiology, Université Paul Sabatier, Toulouse, France

2000-2003 Bachelor’s degree in Cellular Biology and Physiology, Université Paul Sabatier, Toulouse, France

TEACHING

2016-2018 Master in Pharmacology, Université Toulouse III, France. 

2015 Research University for Young Nephrologists, Lyon, France.

2006-2009 Cell Biology, Molecular Biology, Animal Physiology, Histology for medical students and biology student (1st year to 5th year) Université Toulouse III, France and Conservatoire National des Arts et Métiers (CNAM), Toulouse, France

FELLOWSHIPS AND GRANTS

2014 Research subvention for clinical nephrology research, French Society of Nephrology/Genzyme

2012-2013 Postdoctoral Fellowship, FP7 Marie-Curie, Intra-European Mobility

2012-2013 Postdoctoral Fellowship, EMBO/ERA-EDTA

2008-2009 Research Fellowship, Fondation pour la Recherche Médicale

2005-2008 PhD Grant, French Board of Education and Research

PRIZES AND AWARDS

2016 Académie des Sciences Award, The Academy of Sciences, Toulouse, France

2015 Research Award, French Society of Nephrology

2011 Lucien Babonneau Award for Diffusion of the scientific knowledge, The Academy of Sciences, Toulouse, France

SCIENTIFIC SOCIETIES

Société Française de Néphrologie Dialyse et Transplantation (member)

American Society of Nephrology (member)

Femmes & Sciences (member)

Women in Nephrology (member)

DISSEMINATION

Destination labo (2015, 2016, 2017)

Fête de la Science (2015, 2018)

Nuit européennes des chercheurs (2015, 2017, 2018)

ESOF (2018)

Journée des filles et des Femmes en sciences, UNESCO (2018)

Scientific summary

Julie Klein received her PhD from the University Paul Sabatier, Toulouse, France, in 2009. From 2009 to 2014 she worked as a post-doctoral fellow in the field of proteomics and bioinformatics in chronic kidney disease and was recruited as a researcher at the Renal Fibrosis Lab, INSERM U1048, Toulouse in 2014.

Julie Klein main domains of expertise are:

- Bioinformatics tools and databases (http://www.kupkb.org/; http://www.proteasix.org/)

- Clinical proteomics

- Cardiovascular complications of chronic kidney disease

- Mechanisms of chronic kidney disease

- Urinary biomarker

Selected Publications (ORCID ID: 0000-0002-3279-0559):

Klein J, Ramirez-Torres A, Ericsson A, Huang Y, Breuil B, Siwy J, Mischak H, Peng XR, Bascands JL, Schanstra JP. Urinary peptidomics provides a noninvasive humanized readout of diabetic nephropathy in mice. Kidney Int. 2016 Nov;90(5):1045-1055. doi: 10.1016/j.kint.2016.06.023. Epub 2016 Aug 12.

Glorieux G, Mullen W, Duranton F, Filip S, Gayrard N, Husi H, Schepers E, Neirynck N, Schanstra JP, Jankowski J, Mischak H, Argilés À, Vanholder R, Vlahou A, Klein J. New insights in molecular mechanisms involved in chronic kidney disease using high-resolution plasma proteome analysis. Nephrol Dial Transplant. 2015 Nov;30(11):1842-52. doi: 10.1093/ndt/gfv254. Epub 2015 Jul 9.

Klein J, Lacroix C, Caubet C, Siwy J, Zürbig P, Dakna M, Muller F, Breuil B, Stalmach A, Mullen W, Mischak H, Bandin F, Monsarrat B, Bascands JL, Decramer S, Schanstra JP. Fetal urinary peptides to predict postnatal outcome of renal disease in fetuses with posterior urethral valves (PUV). Sci Transl Med. 2013 Aug 14;5(198):198ra106. doi: 10.1126/scitranslmed.3005807.

Klein J, Eales J, Zurbig P, Vlahou T, Mischak H, Stevens R. Proteasix: a tool for automated and large-scale prediction of proteases involved in naturally-occurring peptide generation. Proteomics, 2013 Apr;13(7):1077-82. doi: 10.1002/pmic.201200493. Epub 2013 Feb 26

Klein J, Jupp S, Moulos P, Fernandez M, Buffin-Meyer B, Casemayou A, Chaaya R, Charonis A, Bascands JL, Stevens R, Schanstra JP. The KUPKB: a novel Web application to access multiomics data on kidney disease. FASEB J. 2012 May;26(5):2145-53. doi: 10.1096/fj.11-194381. Epub 2012 Feb 17.