Erick Denamur
  • E-mail :[email]
  • Phone : 33 1 57 27 77 39
  • Location : Paris, France

Scientific topics

Keywords

Last update 2011-03-24 15:23:06.045

Erick Denamur Professsor

Course and current status

Degrees
1991: Ph. D. in Biological Chemistry and Molecular Biology, Paris 11 University
1986: M. D. Amiens Medical School, Picardie University
Academic positions
2000-present: Professor in Biochemistry and Molecular Biology, Xavier Bichat Medical School, Paris 7 University
1994-2000: Associate Professor in Genetics, Xavier Bichat Medical School, Paris 7 University
1989-1991: Assistant Professor in Biochemistry and Molecular Biology, Xavier Bichat Medical School, Paris 7 University
1988-1989: Assistant Professor in Bacteriology, Amiens Medical School, Picardie University
1982-1988: Resident, University Hospital of Amiens
Research training (post doctoral)
2003-present: Director of the INSERM unit E0339 "Ecology and evolution of microorganisms", Xavier Bichat Medical School, Paris, then U722 (January 2005)
1994-2002: Head of the team "Cystic fibrosis" then head of the team "Genetic variability and evolution" at the INSERM unit 120 then 458, Robert Debré hospital, Paris
1993-1994: Researcher at the INSERM unit 120, Robert Debré hospital, Paris
1991-1993: Visiting Fellow, Department of Laboratory Medicine, Howard Hughes Medical Institute, University of California, San Francisco (Pr Y.W. Kan)







Scientific summary

My goal is to bring fundamental evolutionary approach in medical research. After an interest in human genetic diseases, especially cystic fibrosis, I now focus on the infectious diseases where I try to understand, in an ecological and evolutionary perspective, how bacteria become pathogenic and eventually resistant. The bulk of my work is based on Escherichia coli, which is a natural inhabitant of the gut flora of vertebrates, including humans, but also frequently involved in a broad spectrum of intestinal (diarrhoea) and extra intestinal (urinary tract infection, septicemia, meningitis) diseases. The used approach is to reconstruct the evolutionary scenario of bacterial adaptation, including virulence and resistance, using numerous natural isolates from various origins.

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