Principal Investigator
My work focused on the functions of cholinesterases, with specific attention to production and analysis of null mutants of cholinesterases in animal models. I have expertise in the genetic aspects of cholinesterase biosynthesis. I also analyzed the phylogeny of cholinesterases and related proteins, and created the database ESTHER (http://bioweb.supagro.inra.fr/ESTHER/general?what=index) dedicated to the analysis of protein and nucleic acid sequences belonging to the superfamily of alpha/beta hydrolases homologous to cholinesterases