• E-mail :[email]
  • Phone : +33 (0)3 20 43 41 94
  • Location : VILLENEUVE, France
Last update 2022-01-28 14:44:41.796

Isabelle FOURNIER Professor Mass Spectrometry & Proteomics

Course and current status


  • 2015-present      Distinguished Professor & co-director, Laboratory of Proteomics, Inflammatory Response & Mass Spectrometry (PRISM) Inserm U1192, Biology Department, University of Lille (ULille), France,



  • 2017-2020:  Director of the Public/private unit (O’Dreams), Mixed team with the company OCR
  • 2010-2014: Deputy Director, Lab. of Fundamental and Applied Biological Mass Spectrometry, Biology Department, University Lille 1 Science & Technology (ULille 1), France
  • 2009-2015: Full Professor, Biology Department, ULille 1, France
  • 2004-2010: Group Leader, MALDI Imaging Team, Lab. of Annelids Neuroimunology, Biology Department, ULille 1, France (9 full-time equivalent members)
  • 2003-2009: Associate Professor, Faculty of Sciences, Biology Department, ULille 1, France
  • 2001-2003: Postdoctoral fellow, Lab. Annelids Neuroimunology, CNRS UMR8017, ULille 1, France
  • 2000-2001: Postdoctoral fellow, Group of Prof. M. Karas, Department of Chemistry, University J.W. Goethe, Frankfurt-am-Main, Germany


  • 2005: Habilitation à Diriger les Recherches (mandatory diploma to apply for professorship), Biology Department, University Lille 1 Science & Technology (ULille 1), France, Development of MALDI MS Imaging and its Application to Biology
  • 1996-2000: PhD, Laboratory of Organic & Biological Structural Chemistry, Chemistry Department, Univ. Pierre & Marie Curie, Paris, France, Contribution to the Study of Physico-Chemical Mechanisms Involved in the Matrix Assisted Laser/Desorption Ionization Process.
  • 1994-1996: Master’s in Chemistry, Mention Spectrochemistry & Organic Physicochemistry, Chemistry Department, University Pierre & Marie Curie, Paris, France

Scientific summary


Prof. Fournier leads the research axe "Technological Innovation" of PRISM Inserm U1192 Research Unit dedicated to "Technological Innovation". She is also in charge of the coordination of the Clic-Imaging service platform which is certified by the GIS IBISA since 2018 ( She started her research working in the field of fundamental mass spectrometry looking for the fundamental mechanisms of matrix assisted laser desorption ionization (MALDI). This led her to got interested in the methodological developments of MALDI MS for biological applications in proteomics. She created her own group in 2002 thanks to a national starting grant (ACI Jeunes Chercheurs). With her group, she was the first in France to develop MALDI MS imaging and, in 2007, to demonstrate that MALDI MS imaging could be performed on archived formalin-fixed and paraffin-embedded hospital tissue samples. The developments in MALDI MS imaging have been valorized by several patents, which led Professor Fournier to be co-founder of the start-up Imabiotech SAS. In 2009, Professor Fournier was named junior member of the academy of excellence of the Institut Universitaire de France. Since 2010, she has been interested in the development of large-scale proteomics strategies for spatially resolved proteomics. More recently, she has been involved in the development of new instrumentation for real-time in vivo MS analysis for guided surgery and intraoperative diagnosis. Prof. Fournier was a member of the steering committee of the Lille Cancer Center of Excellence (SIRIC OncoLille 2013-2017). She also represented France in the COST BM1104 action dedicated to MS imaging. She is an international expert for many granting agencies, including NWO, DFG, FNRS, Cancer UK, FRNTQ, EU MSCA-IF & MSCA-ITN and, more recently, she was appointed VC for the H2020 FET-OPEN calls. She has supervised 20 PhD students and supervised 8 post-doctoral researchers. She has already coordinated several projects, including regional and national projects, including several ANR, including Starting Grant (2004-2008, ACI Jeunes Chercheurs), ANR PCV Program (BIOSPIM 2007-2010) and REALITY'MS (2014-2018) and FUN MALDI as Co-PI (2009-2013). In 2019, she was awarded a Senior Member position at the IUF (Institut Universitaire de France) for her contribution to the field of clinical mass spectrometry. Since 2021, she is a member of the steering committee of the GIS IBiSA, national structure of technological platforms and resources ( and since 2022 she is Vice President for Doctoral Affairs of the University of Lille.





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