CV Science

Florence APPARAILLY research director

Course and current status

SCIENTIFIC EXPERIENCE

2015-  Team leader at INSERM u1183, Montpellier, France

2011-2014        Research director (DR2), INSERM u844, Montpellier, France

2006-2010        Research associate (CR1), INSERM u844, Montpellier, France

2001-2005        Research associate (CR2), INSERM u475, Montpellier, France

1997-2001        Post-doc. at INSERM u475, Montpellier, France

1996                 Post-doc. at New York University Medical Center, department of Pharmacology, New York, US (Prof. J Schlessinger)

1994-96            Post-doc. at Rockefeller University, Center of Biomedical Research, New York, US (Dr. P Morris)

UNIVERSITY DEGREE COURSE

2004              HDR in Biology, University of Montpellier

1990-1993       PhD in Physiology of Reproduction, University of Paris VI (First class honour

Scientific summary

Florence Apparailly is working since 1997 with the Pr Jorgensen on identifying new therapeutic targets for anti-inflammatory immunotherapy in rheumatoid arthritis. She has a proven track record in gene therapy and animal models of arthritis. Since 2007, she is working on RNAi as an experimental and therapeutic tool to study and regulate physiological and pathological processes in arthritis. She works on miRNAs as novel type of diagnostic and prognosis biomarkers, and on the identification of a miRNA playing a key causal role in RA pathogenesis that might lead to the development of novel efficient anti-inflammatory and anti-osteoclastic  therapeutic strategies.