François Estève MD, PhD Biomedical Engineering, Professor

Course and current status

ESTÈVE François

born in March 23rd 1957 in Montpellier, FRANCE

Professor of Biophysics & Nuclear Medicine (PU-PH 1st class)

Head of the INSERM Unit836/6 Rayonnement Synchrotron et Recherche Médicale RSRM / ID17-ESRF-38043 GRENOBLE and Grenoble Institut of Neurosciences

                  FRANCE

EDUCATION

        Master in Pure Mathematics, University Paul Sabatier - Toulouse 1979

        Medical Doctor (specialist Medical Research), 1993

        Biomedical Engineering PhD, University Joseph Fourier - Grenoble 1993

        Accreditation to lead research 1999

PROFESSIONAL EXPERIENCE

Research activities

MR spectroscopy (proton and phosphorus) and medical imaging started in 1993

Biomedical and medical applications of synchrotron radiation started in 1996

Teaching activities

Coordinator of the Master Engineering for Health and Pharmaceutics (Université Joseph Fourier)

Biophysics, Numerical Imaging and Signal Processing Signal in Medicine university Numerical Imaging and Signal Processing Signal in Biomedical Engineering Masters , MRI and  Synchrotron Radiation Computed Tomography in School of Engineers l’École Nationale Supérieure de Physique de Grenoble (ENSPG)

Hospital activities                              

Acquisition, processing and analyze of proton and phosphorus MR spectroscopy scans in different clinical research protocols. Management of the MR spectroscopy activity

Administrative Activities and scientific coordination

Scientific and administrative heading of the Équipe d’Accueil RSRM

Head of the INSERM U647 RSRM (Rayonnement Synchrotron et Recherche Médicale)

Head of the Team 6 of the INSERM unit 836

Co-chairman with Dr W. Thomlinson of the international  workshop : Medical Applications of Synchrotron Radiation  (March 1-3  2001) in Grenoble MASR2001. Member of the MASR2004-Trieste board. Member of the MASR2007-Sakatoon board, MASR2010-Melbourne board and MASR2012-Shangaï board

Expertise activity

Member of review panels for different research institutions and councils, universities or national research agencies, governments, in France, UK, Australia, Canada.

Member of the GP MED, expert group of the Autorité de Sûreté Nucléaire.

Peer review activity for journals (Phys Med Biol, J Synchro Radiation, Int J Rad Oncol Biol Phys, J Comp Ass Tomo, …)

Scientific summary

Our work was to contribute to the clinical transfer of investigation tools such as MR spectroscopy or synchrotron radiation, both from the world of physics research have become important in brain tumor pathology and generally in clinical research. The use for Medical Research of the advanced technologies sounds to be relevant to the interface Medicine - Physics. We have contributed to the construction and development of medical applications of synchrotron radiation, this tool is now internationally developed. Many lines dedicated to medical research applications of synchrotron radiation are planned or under construction (Japan, Australia, Canada, China...) and the Grenoble route is regularly cited as an example. We believe that we have significantly helped the establishment of an effective interface between Physics and Medicine who has achieved in  few years the reputation and critical mass to be a scientific and medical community dedicated to medical research around exceptional tools. The tool "per se" can not set itself up as science, its optimal use for biomedical research and medicine, is clearly the main goal that we will continue in the future as we  did it in the past.
All our range of training courses and our research work pre-clinical and clinical course is a research-oriented medical carreer. We will continue to invest in these activities through our university hospital and team manager position in a research center.