Scientific topics
Keywords
Thierry Huby INSERM Research Scientist
Course and current status
INSERM Research Scientist 2000 - ... : UMRS_1166 National Institute of Health and Medical Research (INSERM), Paris - France
Postdoctoral Fellow 1997-1999 : Lawrence Berkeley National laboratory, Berkeley - U.S. Department of Energy - University of California; Genome Sciences Department (Edward M Rubin)
PhD Fellow 1993-1997 : National Institute of Health and Medical Research (INSERM), Paris - France (John Chapman/Joëlle Thillet)
Scientific summary
My main research focuses on understanding the role of tissue resident and monocyte-derived macrophages in cholesterol metabolism given particular attention to specific cellular players, such as the scavenger receptor SCARB1, but also, specific tissue macrophage populations such as Kupffer cells. Our experimental approaches mainly involve use of mouse models to target candidate genes and cell types to evaluate their contribution in vivo in maintaining cholesterol homeostasis in the context of cardio-metabolic diseases.
