Scientific topics
Keywords
Daniel Aberdam PhD Molecular genetics
Course and current status
Education
1980: BA in Biology at the P. & M. Curie University Paris VI
1983: Msc (Neurobiology) at Weizmann Institute of Sciences (Rehovot, Israel)
1990: PhD (Genetics) at Weizmann Institute of Sciences (Rehovot, Israel)
1991-1994 : Postdoctoral stage (J.P. Ortonne, Nice France)
Previous Employment
1995-2007: Director of Research INSERM (DR2) at INSERM U364 (Nice, France)
2007- : Director of INSERM U898 (Nice, France)
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EXPERTISE, ADVICES, SOCIETIES
Fields of expertise: stem cells, development, genetics, epithelial cancers, genotoxic stress.
Editorial board member of Stem Cells (2009- )
Editorial board member of Cell Death & Medicine (2010- )
Editorial board member of Stem Cells and Cloning (2008- )
Expert for the French Agency of Biomedicine (2006- )
Expert for the French Parliament on Bioethics (2004- )
Member of AFM Scientific Board (2006- )
Member of Scientific Board for the Programme National de Recherche en Dermatologie (2006- )
Member of Interface Committee INSERM-Dermatology (2002- )
Member of the International Society of Stem Cell Research (2002- )
Member of the Israeli Stem cell society (2007- )
Regular referee for:
- submitted manuscripts to: Nature genetics, Embo J, Embo R., Stem cells, CDD, Mol Cell Biol, J Biol Chem, Oncogene, Exp. Dermatol.
- grant applications to: ACI, ANR, AFM, US-Israel binational grants, NIH, Régions, EEC,...).
Scientific summary
Dr Daniel Aberdam' scientific interests focus on epidermal gene regulation. More recently, his group has focused on the physiopathology of stem cells and designed original cellular models from embryonic stem cells that recapitulate embryonic normal and pathological skin and cornea formation. It allows the characterization of genes and signaling pathways involved in these critical steps, with particular attention on p63 functions and regulation and their involvement in skin defects found in patients affected by human congenital disorders, like ectodermal dysplasia syndromes. This team was the first to demonstrate the ability of pluripotent stem cells to produce a full thickness skin.
Related sites:
Interview by Stem Cells journal:
http://www.stemcellsportal.com/Interviews/an-interview-with-daniel-aberdam.html
Presentation of INSERM U898: http://www.youtube.com/watch?v=El_vMPYNl1g
www2.kenes.com/biomed2009/conference/...cv/Aberdam_Daniel_Bio.pdf
