Scientific topics
Keywords
ITMO
Last update 2024-01-31 12:06:53.637
Vincent GOFFIN PhD Molecular Endocrinology
Course and current status
1986-1994: University of Liege, Belgium.
- 1987: M. Sc., Animal Physiology Lab
- 1993: PhD thesis, Research assistant of the Belgian National Funds for Scientific Research (FNRS), Molecular Biology and Genetic Engineering Lab.
1994-present: Inserm and Université Paris Cité, Faculty of Medicine, Necker site, Paris, France
- 1994-1996: Post-doctoral fellow of the European Community – Marie Curie fellowship, Molecular Endocrinology Lab
- 1996-2005: Associate Professor, Team leader at Molecular Endocrinology Lab
- 2006-present: Professor/Research Director, Head of "PRL/GH Pathophysiology" Lab, Institut Necker Enfants Malades (Inserm Unit 1151)
- Since 2022 : Head of Service Unit 24 / SFR Necker (technological core facilities of Necker site)
Scientific summary
Major interests
- Prostate cancer, benign prostate hyperplasia, and stem/progenitor cells (cell plasticity and therapeutic targeting)
- PRL and GH in human pathophysiology
Major findings
- Discovery of castration-resistant luminal progenitor cells in the mouse prostate and their role in prostate tumorigenesis.
- Development of pure prolactin receptor antagonists, used worldwide in academia since 20 years.
Research tools
Translational approaches (preclinical cell/mouse models, organoids, human biocollections)
