CV Science

giuseppe villani PhD Molecular Biology

Course and current status

                                                     CV 

Name : Giuseppe Villani

 Birth :  March, 9, 1949 in Lungavilla ( Pavia ) , Italy

 Nationality : Italian and French

 Familial situation: married, 2 daugthers

 Personal adress : 71, Avenue Tolosane , 31520, Ramonville St Agne, France

                                        Professional Experience

1968-1973                                             Master Degree in Biochemistry, University of Pavia (Italy). Thesis «Purification of DNA Polymerases from Bacillus subtilis »,  advisor : Prof. A.Falaschi

        1974- 1978                     PhD in Molecular Biology, Free University of Brussels  (Belgium).Thesis « Role of DNA Polymerases in indumutagenesis»,  advisor : Dr. M.Radman

 1978-1981                       Post-doctoral period at the Department of Biochemistry of theUniversity of Stanford (USA), advisor : Prof. I.R.Lehman

 1981                                Assistant professor of Toxicology at the University of Toulouse III (France)

 1982                                                                Admission at the French Institut National de la Santé et de la Recherche Médicale (INSERM)

1991                          September to December : visiting Scientist at the Department of Biochemistry, Beckman Center, Stanford University (USA), in the group of Prof. I R Lehman.

1995                                 Advancement to the degree of Directeur de Recherche INSERM  

2001                                April to June: visiting scientist at the Department of Biochemistry, Beckman Center, Stanford University (USA), in the group of Prof.I R Lehman

                                        Present position

                                 Research Director at the Institut de Pharmacologie et de Biologie Structurale, CNRS- UMR 5089, University Toulouse III, 205, Route de Narbonne-31077 Toulouse cedex 4  France

                                       Awards

1979                                Prix Lacassagne de la Ligue Nationale Contre le Cancer

                                        Editorial responsibilities

 2002-2012                       Editor of the Journal of Biological Chemistry

Scientific summary

We are interested in the molecular mechanisms of replication of damaged DNA.

More precisely we attempt to reconstitute in vitro systems of replication of damaged DNA and we investigate :

- the function of the proteins required for these processes

- the role of DNA polymerase associated proof-reading exonucleaseactivity in  replication of damaged DNA       

- the protein-protein and protein- DNA interactions involved in this process