Scientific topics
Keywords
Yves CAZALS Ph D Auditory impairments : physiopathology and rehabilitation
Course and current status
Profesional cursus (degrees and positions)
- Master in Psychology 1972.
- Master in Physiology 1973.
- PhD Physiology 1983.
- HDR 1986.
- Research Fellow, Institute of Sound and Vibration Research, Université de Southampton, Angleterre, janvier-juin 1974.
- Attaché-assistant de sciences fondamentales, Faculté de Médecine, Bordeaux, octobre 1974-
juillet 1975, octobre 1976- septembre 1978.
- Boursier de la Fondation pour la Recherche médicale, octobre 1978- février 1979.
- Attaché de recherche Inserm, march 1979 - december 1981.
- Research Fellow, Kresge Hearing Research Institute, Université du Michigan, Medical school, Ann Arbor, USA, january-july 1980.
- Chargé de recherche Inserm, january 1982.
- Director by interim of Inserm unit 229, august 1982- august 1983.
- Directeur de recherche Inserm, march 1990.
- Directeur of Inserm unit 9902, january 1999- january2004
Expertises
- Project leader within the European Concerted action "Hearing impairments" European Commission, DG XII, for the project "Objective methods in audiology - Models opf auditory pathologies", 1982 - 1984
- Expert for the evaluation of projects for scientific equipments for Anvar, 1982 - 1994
- Member of the group Inserm Auditory Handicap 1984
- Member of the group on comparative studies among cochlear implants and of the group on Brain Neuromagnetism, French Ministery of Research and Technology 1985.
- Président of the group Audition of the Société Française d'Acoustique 1991-1994, and member of the bureau of this society 1988-1991, et 1994-1996.
- President of the Editing Committee of the Journal d'acoustique 1989.
- Associate editor section Auditory Physiology for the journal Acta Acustica, 1990 until now
- Expert for the follow-up of projects in the TIDE area (Technologies for réhabilitation) for the European commission, DGXIII , 1992-1999
- Contractor for France in the European project Natasha (Telematics Applications programme) 1998-2001
- Expert for the European Commission for evalaution of projects on auditory rehabilitation 5th PRC Ageing and disabilities 2002
- Expert for the French ministery of research for projects on Technologies for Handicaps 2004
- Associate editor for Hearing Research 2004- now
- Expert for the Inserm report on Auditory deficits, 2006
- Expert for the European Commission Report - Scientific Committee on Emerging and Newly Identified Health Risks : Potential health risks of exposure to noise from personal music players and mobile phones including a music playing function. 2008-
Scientific summary
My research activities over the past 35 years have dealt with the pathophysiology of inner ear impairments and rehabilitation.
Main contributions :
Clinical studies
Tinnitus suppression through electrical cochlear stimulation (including a licensed commercialized implant)
Development of a (unichannel) cochlear implant for profound deafness rehabilitation.
Various psycoacoustic/audiologic studies of hearing impairments
Animal experiments
Evaluation of the ototoxicity of various medical drugs : antibiotics, diuretics, aspirin; dose/effects; electrophysiology, pharmacology, histology (chemical, immuno).
Animal model of Meniere's disease : validation through longitudinal electrophysiologic studies, morphological specific features (atrophy of middle and short cilia), pharmacological potential treatments.
Preventive and curative treatments for acoustic trauma in animal experiments.
